| Driver Trucking INC | Transportation and Warehousing | $112,200 | $113,168 | 13 | <$5M | Research |
| Shree Ram Hospitality Group LLC | Accommodation and Food Services | $111,601 | $113,007 | 23 | $7.2M | Research |
| San Jose of Roanoke Rapids, Inc. | Accommodation and Food Services | $111,404 | $94,431 | 11 | <$5M | Research |
| Fairwood Lanes 2 LLC | Arts, Entertainment, and Recreation | $108,962 | $109,668 | 20 | <$5M | Research |
| Fowler Crop Consulting INC | Agriculture, Forestry, Fishing and Hunting | $108,952 | $109,681 | 13 | <$5M | Research |
| Lawrence D. Singer M.d. & Associates PA | Health Care and Social Assistance | $107,100 | $107,713 | 9 | <$5M | Research |
| Powell`s Garage Inc. | Wholesale Trade | $107,000 | $108,217 | 16 | <$5M | Research |
| Howard Yee Dmd PA | Health Care and Social Assistance | $105,000 | $80,382 | 10 | <$5M | Research |
| Bennett Trucking & Logging LLC | Agriculture, Forestry, Fishing and Hunting | $102,271 | $102,817 | 7 | <$5M | Research |
| Howard Yee Dmd PA | Health Care and Social Assistance | $100,000 | $100,992 | 12 | <$5M | Research |
| Bennett Trucking & Logging LLC | Agriculture, Forestry, Fishing and Hunting | $99,702 | $100,825 | 10 | <$5M | Research |
| Carolina Care of Halifax, LLC | Health Care and Social Assistance | $96,955 | $97,771 | 31 | $5.3M | Research |
| Garner Landscaping & Lawn Care, Inc. | Administrative and Support and Waste Management | $95,762 | $96,815 | 16 | <$5M | Research |
| Creekside Animal Hospital, Pllc | Professional, Scientific, and Technical Services | $95,357 | $89,568 | 14 | <$5M | Research |
| Wellman & White Pllc | Professional, Scientific, and Technical Services | $91,833 | $92,313 | 7 | <$5M | Research |
| Halifax Gastroenterology P.c. | Health Care and Social Assistance | $89,100 | $90,011 | 13 | <$5M | Research |
| Dlm Ventures of Roanoke Rapids INC | Accommodation and Food Services | $88,717 | $89,649 | 25 | <$5M | Research |
| 1911 Rapids | Accommodation and Food Services | $86,600 | $87,269 | 19 | $5.9M | Research |
| Wh Pharmacy 1 LLC | Retail Trade | $85,500 | $86,334 | 11 | <$5M | Research |
| Gilbert W. Chichester PA | Professional, Scientific, and Technical Services | $84,530 | $84,955 | 5 | <$5M | Research |
| Spring Life Behavioral Care, LLC | Health Care and Social Assistance | $84,028 | $84,493 | 18 | <$5M | Research |
| Sai Urology PA | Health Care and Social Assistance | $83,400 | $84,351 | 7 | <$5M | Research |
| Shree Ram Hospitality Group, LLC | Accommodation and Food Services | $79,715 | $80,322 | 19 | $5.9M | Research |
| Northeastern Carolina Physical Therapy Inc. | Health Care and Social Assistance | $79,100 | $79,815 | 8 | <$5M | Research |
| Little & Jenkins Rebuilders, Inc. | Other Services (except Public Administration) | $78,440 | $79,083 | 12 | <$5M | Research |