| Boddie-Noell Enterprises INC | Accommodation and Food Services | $10,000,000 | $10,115,556 | 500 | $88.8M | Research |
| Boice-Willis Clinic, P.a. | Health Care and Social Assistance | $4,558,200 | $4,611,632 | 379 | $119.0M | Research |
| North Carolina Wesleyan College, Incorporated | Educational Services | $3,021,500 | $3,056,185 | 366 | N/A | Research |
| Trans-Tech Energy, LLC | Manufacturing | $2,540,500 | $2,571,409 | 156 | $38.1M | Research |
| Freedom Industries INC | Construction | $1,896,577 | $1,912,165 | 143 | $47.0M | Research |
| Freedom Industries, Inc. | Construction | $1,856,300 | $1,866,370 | 143 | $45.2M | Research |
| Opportunities Industrialization Center, Incorporated | Other Services (except Public Administration) | $1,714,770 | $1,667,261 | 167 | N/A | Research |
| Bay Foods INC | Accommodation and Food Services | $1,702,300 | $1,719,796 | 465 | $82.6M | Research |
| Coeco Office Systems INC | Wholesale Trade | $1,377,970 | $1,388,688 | 100 | $30.6M | Research |
| Brewer Foods, INC | Accommodation and Food Services | $1,335,500 | $1,351,341 | 389 | $69.1M | Research |
| Coeco Office Systems INC | Wholesale Trade | $1,259,900 | $1,268,054 | 114 | $34.9M | Research |
| Bht Enterprises LLC | Accommodation and Food Services | $1,095,500 | $1,107,459 | 369 | $65.5M | Research |
| Wade-Cary Enterprises, Inc. | Accommodation and Food Services | $1,020,491 | $1,027,171 | 306 | $54.3M | Research |
| Daughtridge Gas & Oil Company | Mining, Quarrying, and Oil and Gas Extraction | $831,228 | $838,571 | 124 | $7.5M | Research |
| Rocky Mount Family Medical Center, P. A. | Health Care and Social Assistance | $808,800 | $751,057 | 67 | $21.0M | Research |
| Premier Ford Lincoln Mercury INC | Retail Trade | $781,685 | $790,594 | 65 | $16.4M | Research |
| Rocky Mount Academy | Educational Services | $775,400 | $782,616 | 81 | N/A | Research |
| Tri-County Industries, Inc. | Educational Services | $734,400 | $741,968 | 180 | N/A | Research |
| Allred Mechanical Services INC | Construction | $729,000 | $735,946 | 70 | $22.1M | Research |
| Carolina Eagle Distributing, Inc. | Wholesale Trade | $715,200 | $723,127 | 97 | $25.0M | Research |
| Crown Lsp Group INC | Transportation and Warehousing | $702,720 | $705,472 | 83 | $21.1M | Research |
| Hudson Rocky Mount Acquisition, LLC | Retail Trade | $656,800 | $661,101 | 47 | $11.8M | Research |
| The Jay Group Ltd. | Wholesale Trade | $634,435 | $642,841 | 110 | $28.3M | Research |
| Jr's Maintenance Service INC | Other Services (except Public Administration) | $625,000 | $630,260 | 67 | $13.1M | Research |
| Davenport Motor Company of Rocky Mount, Inc. | Retail Trade | $624,900 | $629,014 | 45 | $11.3M | Research |