| Anomaly Squared, Inc. | Administrative and Support and Waste Management | $1,092,600 | $1,104,035 | 247 | $46.7M | Research |
| Archdale Nursing Center, Inc. | Health Care and Social Assistance | $761,100 | $766,563 | 130 | $22.1M | Research |
| Greatest Generation, Inc. | Health Care and Social Assistance | $686,800 | $693,141 | 110 | $18.7M | Research |
| Trinity Furniture Inc. | Manufacturing | $612,385 | $618,308 | 84 | $22.0M | Research |
| Trinity Furniture, Inc. | Manufacturing | $612,385 | $617,435 | 84 | $22.0M | Research |
| Housand Corporation | Accommodation and Food Services | $580,860 | $585,571 | 86 | $15.3M | Research |
| American Concrete Construction Inc. | Construction | $577,005 | $582,538 | 50 | $11.6M | Research |
| American Concrete Construction, Inc. | Construction | $518,435 | $521,191 | 50 | $11.6M | Research |
| Housand Corporation | Accommodation and Food Services | $414,900 | $419,276 | 86 | $15.3M | Research |
| Wilder Effects LLC | Construction | $410,322 | $0 | 20 | $6.1M | Research |
| Martin & Rush Machining Inc. | Manufacturing | $294,590 | $296,333 | 31 | $7.6M | Research |
| Martin & Rush Machining, Inc. | Manufacturing | $294,590 | $296,438 | 32 | $7.8M | Research |
| Danny Eaton Plumbing, LLC | Construction | $218,065 | $220,282 | 30 | $9.5M | Research |
| Franchi Trucking INC | Transportation and Warehousing | $204,735 | $206,962 | 20 | <$5M | Research |
| Larry E Brown Jr Insurance Agency INC | Finance and Insurance | $92,886 | $93,511 | 10 | <$5M | Research |
| Larry E Brown Jr Insurance Agency INC | Finance and Insurance | $88,506 | $88,870 | 9 | <$5M | Research |
| Bobby Labonte Enterprises, Inc. | Arts, Entertainment, and Recreation | $86,042 | $86,575 | 11 | <$5M | Research |
| M&j Welding INC | Manufacturing | $75,617 | $76,640 | 6 | $6.0M | Research |
| Trin-Dale Children Center | Health Care and Social Assistance | $72,888 | $73,545 | 15 | <$5M | Research |
| Three in One Investments, LLC | Real Estate and Rental and Leasing | $58,210 | $58,832 | 8 | <$5M | Research |
| Durham Racing Engines Inc. | Other Services (except Public Administration) | $51,245 | $51,502 | 7 | <$5M | Research |
| Durham Racing Engines, Inc. | Other Services (except Public Administration) | $51,245 | $51,769 | 7 | <$5M | Research |
| Hillsville Hardware, LLC | Retail Trade | $43,463 | $43,988 | 7 | <$5M | Research |
| Elite Air Systems LLC | Construction | $38,445 | $38,608 | 4 | <$5M | Research |
| Peace Electric Company LLC | Construction | $38,200 | $38,598 | 12 | <$5M | Research |