| Ashe Services for Aging INC | Health Care and Social Assistance | $630,085 | $637,366 | 121 | $19.6M | AI Deep Dive |
| Dr. Pepper Bottling Company of West Jefferson North Carolina | Manufacturing | $578,500 | $584,887 | 84 | $29.6M | AI Deep Dive |
| Northwestern Emergency Vehicles Inc. | Health Care and Social Assistance | $388,531 | $391,905 | 37 | $6.0M | AI Deep Dive |
| Northwestern Emergency Vehicle | Retail Trade | $355,776 | $357,959 | 36 | $9.4M | AI Deep Dive |
| Zuryc INC | Professional, Scientific, and Technical Services | $331,398 | $336,111 | 23 | <$5M | AI Deep Dive |
| Boondocks Brewing LLC | Accommodation and Food Services | $328,212 | $330,982 | 45 | $14.1M | AI Deep Dive |
| Ashe County Ford, INC | Retail Trade | $323,215 | $325,900 | 38 | $9.6M | AI Deep Dive |
| Tri County Paving | Manufacturing | $301,695 | $305,617 | 43 | $42.6M | AI Deep Dive |
| Sterling Restaurants INC | Administrative and Support and Waste Management | $275,700 | $256,572 | 58 | $11.0M | AI Deep Dive |
| Ashe Medics, LP | Administrative and Support and Waste Management | $252,300 | $255,783 | 44 | $8.3M | AI Deep Dive |
| West Jefferson Chevrolet LLC | Administrative and Support and Waste Management | $242,900 | $244,540 | 27 | $5.1M | AI Deep Dive |
| Boondocks Brewing, LLC | Accommodation and Food Services | $234,437 | $237,122 | 45 | $8.0M | AI Deep Dive |
| Cobble Creek Lumber LLC | Manufacturing | $194,400 | $192,967 | 24 | $23.8M | AI Deep Dive |
| Cobble Creek Lumber Llc. | Manufacturing | $191,293 | $194,351 | 23 | $22.8M | AI Deep Dive |
| Carolina Timberworks, LLC | Manufacturing | $179,300 | $183,320 | 12 | $11.9M | AI Deep Dive |
| Shatley Construction Co, INC | Construction | $172,665 | $174,075 | 30 | $9.1M | AI Deep Dive |
| Shatley Construction Co INC | Construction | $172,665 | $173,437 | 25 | $7.6M | AI Deep Dive |
| Parker Tie Company, INC | Retail Trade | $172,436 | $174,515 | 32 | $6.6M | AI Deep Dive |
| Reeves Law Firm, Pllc | Professional, Scientific, and Technical Services | $155,923 | $157,503 | 12 | <$5M | AI Deep Dive |
| Newburg Corners Cheese Inc. DBA Ashe County Cheese Company | Manufacturing | $141,700 | $142,971 | 24 | $8.5M | AI Deep Dive |
| Reeves Law Firm Pllc | Professional, Scientific, and Technical Services | $141,553 | $142,205 | 12 | <$5M | AI Deep Dive |
| Global Manufacturing Services Inc. | Manufacturing | $126,275 | $126,752 | 20 | $5.2M | AI Deep Dive |
| Boone Family Funeral Home INC | Other Services (except Public Administration) | $126,100 | $84,940 | 10 | <$5M | AI Deep Dive |
| Guion & Lyle Enterprises LLC | Accommodation and Food Services | $121,615 | $122,188 | 37 | $6.6M | AI Deep Dive |
| Learning Thru Play, Inc. | Health Care and Social Assistance | $120,342 | $121,432 | 23 | <$5M | AI Deep Dive |