| Carolina West Wireless, Inc. | Information | $1,654,177 | $1,669,570 | 125 | $21.0M |  Research |
| Wilkes Telephone Membership Corp | Information | $1,631,819 | $1,638,799 | 77 | $12.9M | Research |
| Steve C Davis, Inc. | Health Care and Social Assistance | $693,700 | $699,866 | 42 | $9.7M | Research |
| Church and Church Lumber, LLC | Administrative and Support and Waste Management | $620,700 | $624,907 | 91 | $17.2M | Research |
| Church & Church Lumber Company LLC | Manufacturing | $615,432 | $610,668 | 83 | $82.3M | Research |
| Suncrest Farms Country Ham INC | Manufacturing | $594,115 | $572,456 | 119 | $42.0M | Research |
| Martin Roofing Services, Inc. | Administrative and Support and Waste Management | $475,300 | $479,974 | 55 | $10.4M | Research |
| Huffbo, LLC | Accommodation and Food Services | $473,700 | $477,963 | 150 | $26.6M | Research |
| Wilcox Marketing INC | Wholesale Trade | $443,300 | $445,997 | 43 | $11.1M | Research |
| Accordius Health at Wilkesboro LLC | Health Care and Social Assistance | $438,938 | $0 | 50 | $8.5M | Research |
| Martin Roofing Services Inc. | Construction | $433,795 | $436,374 | 52 | $17.1M | Research |
| Riverstreet Management Services, LLC | Information | $356,752 | $358,655 | 24 | <$5M | Research |
| Appalachian Lumber Company INC | Manufacturing | $347,300 | $349,162 | 54 | $14.1M | Research |
| Interconnect Products & Services, INC | Professional, Scientific, and Technical Services | $333,120 | $335,675 | 39 | $8.1M | Research |
| Cajun Foods of America, Inc. | Administrative and Support and Waste Management | $325,700 | $329,111 | 47 | $8.9M | Research |
| Premier Chevrolet Buick, Inc. | Retail Trade | $321,500 | $323,949 | 37 | $9.3M | Research |
| Interconnect Products and Services Inc. | Construction | $307,236 | $310,056 | 39 | $12.8M | Research |
| Cajun Foods of America Inc. | Accommodation and Food Services | $302,550 | $304,786 | 58 | $10.3M | Research |
| Blue Ridge Tractor Company Incorporated | Other Services (except Public Administration) | $249,800 | $252,579 | 22 | <$5M | Research |
| Mb Automotive Inc. | Retail Trade | $241,641 | $242,925 | 21 | $5.3M | Research |
| Mb Automotive INC | Retail Trade | $223,700 | $225,833 | 24 | $6.0M | Research |
| Timothy D. Welborn P.a. | Professional, Scientific, and Technical Services | $218,700 | $220,468 | 18 | <$5M | Research |
| Barnes & Severt Lumber Co., INC | Manufacturing | $205,760 | $208,218 | 27 | $26.8M | Research |
| Concorde Financial Resources LLC | Administrative and Support and Waste Management | $197,700 | $200,166 | 13 | <$5M | Research |
| Jodi Province Counseling Services Pllc | Health Care and Social Assistance | $188,207 | $190,981 | 23 | <$5M | Research |