| Sheyenne Tooling & Manufacturi | Manufacturing | $666,661 | $670,953 | 58 | $15.2M |  Research |
| Cooperstown Medical Center | Health Care and Social Assistance | $563,910 | $570,787 | 45 | N/A | Research |
| Griggs County Care Center | Health Care and Social Assistance | $494,507 | $500,537 | 65 | N/A | Research |
| Right-A-Way Applicators, Inc. | Agriculture, Forestry, Fishing and Hunting | $424,200 | $426,548 | 31 | <$5M | Research |
| Somerville Enterprises INC | Manufacturing | $360,739 | $362,111 | 31 | $7.6M | Research |
| Posi-Lock Puller, Inc. | Manufacturing | $296,540 | $535,118 | 37 | $9.0M | Research |
| Aerial Timber Applicators, Inc. | Agriculture, Forestry, Fishing and Hunting | $235,000 | $101,456 | 15 | <$5M | Research |
| Cooperstown Implement Company, INC | Wholesale Trade | $150,600 | $151,479 | 12 | <$5M | Research |
| Abraham Generator Sales Company | Retail Trade | $132,700 | $134,012 | 7 | <$5M | Research |
| Dynaband LLC | Administrative and Support and Waste Management | $94,924 | $95,264 | 12 | <$5M | Research |
| Reiten Inc. | Manufacturing | $84,311 | $84,627 | 6 | <$5M | Research |
| Reiten, INC | Manufacturing | $84,300 | $84,698 | 7 | <$5M | Research |
| Christian Automotive Group Inc. | Retail Trade | $82,585 | $83,048 | 11 | <$5M | Research |
| Miller's Super Markets, Inc. | Retail Trade | $74,400 | $74,919 | 18 | <$5M | Research |
| Cooperstown Veterinary Clinic Ltd | Professional, Scientific, and Technical Services | $69,755 | $70,185 | 6 | <$5M | Research |
| Erickson Ag Advantage, Inc. | Agriculture, Forestry, Fishing and Hunting | $58,500 | $58,965 | 8 | <$5M | Research |
| Brager Disposal Service INC | Administrative and Support and Waste Management | $53,471 | $53,722 | 5 | <$5M | Research |
| Agrisales, Inc. | Wholesale Trade | $50,600 | $26,849 | 4 | <$5M | Research |
| Coachman | Accommodation and Food Services | $40,290 | $40,483 | 15 | <$5M | Research |
| The Cooperstown Bible Camp Association of the Evangelical Fr | Other Services (except Public Administration) | $34,723 | $34,873 | 12 | N/A | Research |
| The Cooperstown Bible Camp Association of the Evangelical Fr | Other Services (except Public Administration) | $34,700 | $34,862 | 27 | N/A | Research |
| Cooperstown Community Activities Authority | Health Care and Social Assistance | $34,027 | $34,132 | 9 | N/A | Research |
| Timothy Soma | Agriculture, Forestry, Fishing and Hunting | $33,958 | $34,160 | 3 | <$5M | Research |
| Timothy Soma | Agriculture, Forestry, Fishing and Hunting | $33,958 | $34,309 | 3 | <$5M | Research |
| Cooperstown Community Activities Authority | Health Care and Social Assistance | $33,800 | $33,986 | 12 | N/A | Research |