| West River Regional Medical Center | Health Care and Social Assistance | $2,583,600 | $2,617,330 | 247 | N/A |  Research |
| Western Horizons Living Centers | Health Care and Social Assistance | $406,400 | $411,220 | 49 | N/A | Research |
| Robertson Metal Recycling LLC | Wholesale Trade | $228,948 | $231,046 | 15 | <$5M | Research |
| Robertson Metal Recycling, Llc. | Wholesale Trade | $228,948 | $230,875 | 13 | <$5M | Research |
| West River Veterinary Clinic | Professional, Scientific, and Technical Services | $205,900 | $207,501 | 17 | <$5M | Research |
| Rz Motors Inc. | Retail Trade | $166,300 | $167,884 | 19 | <$5M | Research |
| Kennedy Supermarkets, INC | Retail Trade | $158,400 | $159,249 | 21 | $5.2M | Research |
| Agpro Machinery Sales & Service LLC | Wholesale Trade | $149,915 | $150,431 | 16 | <$5M | Research |
| Valle Grande Ranch & Feeders | Agriculture, Forestry, Fishing and Hunting | $122,900 | $124,230 | 10 | <$5M | Research |
| Clarence Archibald | Agriculture, Forestry, Fishing and Hunting | $103,490 | $104,125 | 10 | <$5M | Research |
| Agpro Machinery Sales & Service, LLC | Wholesale Trade | $98,500 | $99,247 | 10 | <$5M | Research |
| Rusch Land & Cattle Co LLC | Agriculture, Forestry, Fishing and Hunting | $90,494 | $91,070 | 17 | <$5M | Research |
| T2 Honey Company LLC | Agriculture, Forestry, Fishing and Hunting | $74,616 | $75,265 | 13 | <$5M | Research |
| Grand River Honey Company | Agriculture, Forestry, Fishing and Hunting | $69,969 | $70,391 | 7 | <$5M | Research |
| Grand River Honey Co. | Agriculture, Forestry, Fishing and Hunting | $61,000 | $61,344 | 5 | <$5M | Research |
| Melling & Roseland Law, P.c. | Professional, Scientific, and Technical Services | $60,400 | $60,848 | 5 | <$5M | Research |
| Rusch Land & Cattle Co LLC | Agriculture, Forestry, Fishing and Hunting | $59,500 | $59,907 | 12 | <$5M | Research |
| Melling & Roseland Law PC | Professional, Scientific, and Technical Services | $58,968 | $59,451 | 5 | <$5M | Research |
| Air Dakota Flite INC | Transportation and Warehousing | $53,100 | $53,368 | 8 | <$5M | Research |
| Air Dakota Flite, Inc. | Transportation and Warehousing | $53,100 | $53,363 | 8 | <$5M | Research |
| Mirror Lake Lodge | Accommodation and Food Services | $51,500 | $51,913 | 5 | <$5M | Research |
| David Parrill Construction, LLC | Construction | $46,000 | $46,346 | 4 | <$5M | Research |
| Mark W Nelson DDS | Health Care and Social Assistance | $38,912 | $39,172 | 3 | <$5M | Research |
| Pastime Bar & Lounge INC | Accommodation and Food Services | $37,520 | $37,738 | 12 | <$5M | Research |
| Ehlers Trucking, Inc. | Transportation and Warehousing | $37,100 | $37,307 | 3 | <$5M | Research |