| Combs Heating and Cooling | Construction | $151,955 | $153,103 | 15 | <$5M | AI Deep Dive |
| Cse and E, LLC | Construction | $151,800 | $152,470 | 18 | $5.7M | AI Deep Dive |
| Detillion Landscaping Co. | Administrative and Support and Waste Management | $151,240 | $152,404 | 22 | <$5M | AI Deep Dive |
| Studio Suites by Christopher Ltd | Accommodation and Food Services | $150,553 | $151,625 | 20 | $6.3M | AI Deep Dive |
| Knauff's Pizza, LLC | Accommodation and Food Services | $150,532 | $0 | 67 | $11.9M | AI Deep Dive |
| D.e. Huddleston, INC | Construction | $149,278 | $150,406 | 26 | $29.6M | AI Deep Dive |
| Affordable Air | Construction | $148,330 | $149,484 | 16 | $5.1M | AI Deep Dive |
| Herlihy Moving and Storage Inc. | Transportation and Warehousing | $146,009 | $146,966 | 18 | <$5M | AI Deep Dive |
| Friel and Associates LLC | Professional, Scientific, and Technical Services | $143,000 | $143,874 | 24 | <$5M | AI Deep Dive |
| Big Bear Creek LLC | Accommodation and Food Services | $142,740 | $143,390 | 18 | <$5M | AI Deep Dive |
| Ch Family Investments Ii, LLC | Accommodation and Food Services | $140,710 | $141,668 | 48 | $8.5M | AI Deep Dive |
| Ch Investments II LLC | Accommodation and Food Services | $140,233 | $140,906 | 25 | <$5M | AI Deep Dive |
| Chillicothe Motel Partnership, Ltd | Accommodation and Food Services | $139,530 | $140,482 | 22 | $6.9M | AI Deep Dive |
| Chester Eye Center INC | Health Care and Social Assistance | $138,700 | $176,782 | 23 | $5.4M | AI Deep Dive |
| M and W Industrial Services INC | Professional, Scientific, and Technical Services | $138,090 | $138,687 | 15 | <$5M | AI Deep Dive |
| Hana Steak House Inc. | Accommodation and Food Services | $136,458 | $137,498 | 26 | <$5M | AI Deep Dive |
| Crispie Creme of Chillicothe INC | Accommodation and Food Services | $135,073 | $135,759 | 42 | $7.5M | AI Deep Dive |
| Crispie Creme | Accommodation and Food Services | $134,765 | $135,939 | 37 | $6.6M | AI Deep Dive |
| Chillicothe Packing Corporation | Administrative and Support and Waste Management | $134,325 | $135,054 | 17 | <$5M | AI Deep Dive |
| Chillicothe Packaging Corporation | Manufacturing | $134,300 | $135,017 | 17 | $16.9M | AI Deep Dive |
| Pour House at Machinery Hall, Inc. | Accommodation and Food Services | $133,100 | $163,460 | 39 | $6.9M | AI Deep Dive |
| Peared Creation, LLC | Manufacturing | $132,347 | $134,130 | 16 | <$5M | AI Deep Dive |
| Corcoran Farms Partnership | Agriculture, Forestry, Fishing and Hunting | $132,174 | $133,239 | 13 | <$5M | AI Deep Dive |
| Vest Towing & Automotive Service LLC | Transportation and Warehousing | $130,132 | $131,086 | 17 | <$5M | AI Deep Dive |
| We Bee Sub and Company Inc. | Accommodation and Food Services | $130,000 | $131,168 | 29 | $5.1M | AI Deep Dive |