| Community Home Health Care, Inc. | Health Care and Social Assistance | $243,862 | $246,561 | 70 | $12.0M | AI Deep Dive |
| Jackson Vault Co. | Manufacturing | $215,000 | $217,066 | 29 | $28.8M | AI Deep Dive |
| Jackson Vault Company | Manufacturing | $210,614 | $211,895 | 34 | $33.7M | AI Deep Dive |
| The Ironton Four INC | Accommodation and Food Services | $207,994 | $209,601 | 30 | $5.3M | AI Deep Dive |
| Cielec Proctorville LLC | Accommodation and Food Services | $194,200 | $196,158 | 53 | $9.4M | AI Deep Dive |
| J & M Maynard Enterprize | Manufacturing | $174,700 | $175,714 | 20 | $5.2M | AI Deep Dive |
| Mcd Investments | Real Estate and Rental and Leasing | $173,700 | $175,500 | 13 | <$5M | AI Deep Dive |
| J & M Maynard Enterprises INC | Manufacturing | $169,800 | $170,418 | 21 | $5.5M | AI Deep Dive |
| Pdi of Ironton, INC | Wholesale Trade | $158,600 | $160,334 | 15 | <$5M | AI Deep Dive |
| Ironton Oh 0313 LLC | Accommodation and Food Services | $153,294 | $154,277 | 18 | $5.6M | AI Deep Dive |
| Southern Ohio Trenching & Excavating, INC | Construction | $149,200 | $150,033 | 11 | <$5M | AI Deep Dive |
| Southern Ohio Trenching & Excavating, INC | Construction | $149,200 | $149,880 | 9 | <$5M | AI Deep Dive |
| Idox3 LLC | Health Care and Social Assistance | $142,563 | $143,250 | 23 | <$5M | AI Deep Dive |
| Idox3, LLC | Health Care and Social Assistance | $139,848 | $140,622 | 13 | <$5M | AI Deep Dive |
| St Joseph St Lawrence | Educational Services | $137,800 | $138,608 | 33 | N/A | AI Deep Dive |
| Gtl Lumber INC | Wholesale Trade | $136,805 | $138,055 | 24 | $7.4M | AI Deep Dive |
| From Rax to Rich's INC | Accommodation and Food Services | $130,400 | $131,633 | 28 | <$5M | AI Deep Dive |
| Bartram Brothers INC | Retail Trade | $126,500 | $127,192 | 40 | $10.0M | AI Deep Dive |
| The Ironton Four, INC DBA Frisch's Big Boy | Accommodation and Food Services | $125,000 | $126,038 | 56 | $9.9M | AI Deep Dive |
| Phillips Funeral Home, INC | Other Services (except Public Administration) | $122,900 | $123,515 | 20 | <$5M | AI Deep Dive |
| Double B LLC | Accommodation and Food Services | $121,236 | $122,573 | 20 | <$5M | AI Deep Dive |
| Close to Home IV Assisted Living, Inc. | Health Care and Social Assistance | $118,800 | $119,822 | 23 | <$5M | AI Deep Dive |
| Industrial Sanitation, Inc. | Manufacturing | $112,700 | $113,780 | 16 | $15.9M | AI Deep Dive |
| Ironton, Oh 0313 LLC | Accommodation and Food Services | $109,500 | $110,232 | 18 | $5.6M | AI Deep Dive |
| Appalachian Mechanical LLC | Other Services (except Public Administration) | $109,340 | $110,269 | 35 | $7.5M | AI Deep Dive |