| Ohio Valley Medical Center, LLC | Health Care and Social Assistance | $3,004,000 | $3,038,880 | 235 | $41.8M |  Research |
| Benjamin Steel Company, Inc. | Wholesale Trade | $2,771,375 | $2,807,669 | 221 | $67.7M | Research |
| Arc Staffing Solutions, LLC | Administrative and Support and Waste Management | $2,400,800 | $2,147,629 | 249 | $39.2M | Research |
| Tri-State Forest Products, Inc. | Wholesale Trade | $2,219,300 | $2,245,871 | 179 | $54.8M | Research |
| Rocking Horse Childrens Health | Health Care and Social Assistance | $2,176,900 | $1,917,160 | 172 | N/A | Research |
| Parker Trutec, Inc. | Manufacturing | $2,141,200 | $2,165,824 | 460 | $112.4M | Research |
| Jm Consolidated Industries LLC | Manufacturing | $2,019,437 | $2,041,955 | 167 | $43.7M | Research |
| Ohio Valley Medical Center LLC | Health Care and Social Assistance | $1,995,500 | $2,005,422 | 229 | $45.4M | Research |
| Emergent Enterprises LLC | Administrative and Support and Waste Management | $1,995,000 | $2,017,278 | 500 | $78.7M | Research |
| Code Blue, LLC | Finance and Insurance | $1,991,600 | $2,006,114 | 205 | $90.2M | Research |
| Carrillo Staffing Solutions LLC | Administrative and Support and Waste Management | $1,798,887 | $1,814,277 | 317 | $49.9M | Research |
| Mental Health Services Or Clark County, INC | Health Care and Social Assistance | $1,484,650 | $1,493,970 | 190 | $33.8M | Research |
| Rollins Moving & Storage, Inc. | Transportation and Warehousing | $1,390,800 | $1,399,907 | 95 | $24.1M | Research |
| Rollins Moving & Storage INC | Transportation and Warehousing | $1,390,800 | $1,397,278 | 95 | $24.1M | Research |
| Pentaflex Inc. | Manufacturing | $1,350,000 | $1,359,505 | 111 | $27.1M | Research |
| Pentaflex INC | Manufacturing | $1,330,237 | $1,346,569 | 84 | $22.0M | Research |
| Am - Pm Employment LLC | Administrative and Support and Waste Management | $1,301,500 | $1,316,904 | 252 | $39.7M | Research |
| The Champion Company | Manufacturing | $1,235,081 | $1,244,550 | 81 | $80.3M | Research |
| Ohio Stamping & Machine LLC | Manufacturing | $1,226,507 | $1,237,529 | 88 | $23.0M | Research |
| Meva Formwork Systems, Inc. | Retail Trade | $1,094,700 | $1,110,786 | 90 | $14.0M | Research |
| Tac Industries, Inc. | Health Care and Social Assistance | $1,056,750 | $725,032 | 207 | N/A | Research |
| Morgal Machine Tool Co. | Manufacturing | $1,043,653 | $869,295 | 87 | $22.8M | Research |
| Morgal Machine Tool Co. | Manufacturing | $1,043,652 | $1,050,028 | 87 | $22.8M | Research |
| Esterline & Sons Mfg. Co., LLC | Manufacturing | $955,900 | $963,442 | 77 | $20.2M | Research |
| D & K Construction LLC | Construction | $938,879 | $944,747 | 66 | $22.5M | Research |