| Wooster Ophthalmologists, INC | Health Care and Social Assistance | $481,900 | $486,732 | 57 | $13.4M |  Research |
| Graser Equipment Co Limited | Manufacturing | $465,632 | $468,982 | 39 | $10.2M | Research |
| Underwood Motors INC | Retail Trade | $460,200 | $463,975 | 39 | $9.8M | Research |
| Few Automotive Glass Applications INC | Manufacturing | $459,100 | $462,033 | 54 | $14.1M | Research |
| Built Rite Box & Crate INC | Manufacturing | $453,982 | $458,219 | 46 | $45.6M | Research |
| Wooster Ophthlmoloigists INC | Health Care and Social Assistance | $444,400 | $447,856 | 58 | $13.6M | Research |
| Frontz Drilling INC | Construction | $423,400 | $426,505 | 30 | $9.3M | Research |
| Albright Welding Supply Co., Inc. | Wholesale Trade | $422,655 | $425,612 | 35 | $10.7M | Research |
| Central Farm & Garden INC | Wholesale Trade | $418,738 | $422,658 | 44 | $11.3M | Research |
| Engineering Associates, Inc. | Professional, Scientific, and Technical Services | $418,700 | $424,259 | 24 | <$5M | Research |
| Kevsev Auto LLC | Retail Trade | $418,537 | $422,699 | 42 | $10.6M | Research |
| Wooster International Cars | Retail Trade | $412,300 | $415,519 | 48 | $12.1M | Research |
| Nick Amster INC | Health Care and Social Assistance | $411,800 | $413,470 | 150 | N/A | Research |
| Nick Amster, INC | Health Care and Social Assistance | $411,800 | $415,918 | 222 | N/A | Research |
| Young Men's Christian Association of Wayne County | Other Services (except Public Administration) | $407,400 | $408,885 | 118 | N/A | Research |
| The Young Men's Christian Association of Wayne County | Health Care and Social Assistance | $407,400 | $409,811 | 82 | N/A | Research |
| Smetzer's Tire Centers, INC | Retail Trade | $385,800 | $390,108 | 11 | <$5M | Research |
| Keim Concrete LLC | Construction | $383,300 | $337,408 | 24 | $5.6M | Research |
| Xcess Limited | Retail Trade | $375,100 | $377,916 | 86 | $20.2M | Research |
| Becker Farms LLC | Transportation and Warehousing | $373,590 | $376,029 | 28 | $5.6M | Research |
| Anazao Community Partners | Health Care and Social Assistance | $370,200 | $372,411 | 53 | N/A | Research |
| Anazao Community Partners | Health Care and Social Assistance | $370,200 | $372,087 | 46 | N/A | Research |
| Wayne Automotive Group LLC | Other Services (except Public Administration) | $369,600 | $373,717 | 39 | $7.6M | Research |
| Netops Consulting LLC | Professional, Scientific, and Technical Services | $334,019 | $337,081 | 33 | $6.8M | Research |
| Becker Farms LLC | Agriculture, Forestry, Fishing and Hunting | $332,800 | $335,555 | 28 | <$5M | Research |