| Quality Integrated Services Inc. | Professional, Scientific, and Technical Services | $10,000,000 | $10,110,556 | 500 | $70.0M |  Research |
| Hitch Enterprises INC | Agriculture, Forestry, Fishing and Hunting | $3,335,900 | $3,375,565 | 288 | $47.1M | Research |
| Hitch Enterprises Inc. | Agriculture, Forestry, Fishing and Hunting | $2,000,000 | $2,010,411 | 117 | $19.1M | Research |
| Shawnee Development LLC | Arts, Entertainment, and Recreation | $1,053,518 | $1,058,973 | 156 | $21.8M | Research |
| Shawnee Development, LLC DBA Golden Mesa Casino | Arts, Entertainment, and Recreation | $966,300 | $979,299 | 157 | $22.0M | Research |
| Memorial Hospital of Texas County | Health Care and Social Assistance | $958,356 | $960,486 | 110 | $21.8M | Research |
| Memorial Hospital Texas County Authority | Health Care and Social Assistance | $865,200 | $869,694 | 100 | $19.8M | Research |
| Trunchbull Service, LLC | Construction | $696,000 | $702,032 | 66 | $24.7M | Research |
| Trunch Bull Services LLC | Other Services (except Public Administration) | $696,000 | $701,587 | 80 | $17.2M | Research |
| Cri Feeders of Guymon, LLC | Agriculture, Forestry, Fishing and Hunting | $568,742 | $572,263 | 50 | <$5M | Research |
| Dr. W.f. & Mada Dunaway Manor of Guymon | Health Care and Social Assistance | $474,428 | $476,906 | 86 | N/A | Research |
| Dr Wf & Mada Dunaway Manor Nursing Home of Guymon Ok, Inc. | Health Care and Social Assistance | $474,400 | $477,141 | 90 | N/A | Research |
| Stanfield Printing Company, INC | Retail Trade | $394,559 | $396,992 | 61 | $13.2M | Research |
| Davis Hospitality INC | Accommodation and Food Services | $288,400 | $289,794 | 60 | $10.7M | Research |
| Specialty Clinics of St Anne LLC | Health Care and Social Assistance | $269,196 | $270,953 | 26 | $8.2M | Research |
| Speciality Clinics of St. Anne P.l.l.c. | Health Care and Social Assistance | $269,100 | $270,909 | 26 | $8.2M | Research |
| Kode Novus I LLC | Utilities | $209,100 | $83,425 | 17 | N/A | Research |
| Davis Hospitality INC | Accommodation and Food Services | $207,100 | $208,901 | 79 | $14.0M | Research |
| Gigot Agra Products, Inc. | Wholesale Trade | $202,500 | $204,407 | 22 | $6.7M | Research |
| Panhandle Counseling and Health Center, Inc. | Health Care and Social Assistance | $193,300 | $194,443 | 22 | N/A | Research |
| Oakes & Associates Certified Public Accountants P.c. | Professional, Scientific, and Technical Services | $188,100 | $189,788 | 9 | <$5M | Research |
| Oakes & Associates Certified Public Accountants, P.c. | Professional, Scientific, and Technical Services | $188,100 | $189,485 | 14 | <$5M | Research |
| Guymon Physical Therapy & Wellness | Health Care and Social Assistance | $177,300 | $178,315 | 19 | $5.1M | Research |
| Landes Management Inc. | Accommodation and Food Services | $161,700 | $163,339 | 37 | $6.6M | Research |
| Cmml Investments LLC | Retail Trade | $155,900 | $157,416 | 17 | <$5M | Research |