| Sisterly Care Health Services, LLC | Health Care and Social Assistance | $2,865,245 | $2,897,718 | 500 | $85.6M |  Research |
| Family Health Center of Southern Oklahoma INC | Health Care and Social Assistance | $1,356,800 | $1,364,049 | 100 | N/A | Research |
| Victory Professional Management, Inc. | Health Care and Social Assistance | $1,017,400 | $1,022,854 | 109 | $18.7M | Research |
| N & S Associates, LLC | Management of Companies and Enterprises | $331,200 | $335,056 | 32 | $5.3M | Research |
| Complete Home Health of Tishomingo | Health Care and Social Assistance | $310,382 | $314,003 | 38 | $8.8M | Research |
| Blue River Healthcare INC | Health Care and Social Assistance | $258,653 | $260,298 | 47 | $8.0M | Research |
| Canyon Welding Service Inc. | Other Services (except Public Administration) | $206,570 | $207,725 | 13 | <$5M | Research |
| Canyon Welding Service INC | Other Services (except Public Administration) | $206,500 | $207,971 | 15 | <$5M | Research |
| Johnston County Ems | Health Care and Social Assistance | $142,700 | $143,739 | 26 | N/A | Research |
| Ron Austin Dds, INC | Health Care and Social Assistance | $127,600 | $128,692 | 9 | <$5M | Research |
| Tishomingo Sdi LLC | Accommodation and Food Services | $125,348 | $126,371 | 31 | $5.5M | Research |
| Tapematics, Inc. | Manufacturing | $113,000 | $113,706 | 18 | <$5M | Research |
| Tapematics INC | Manufacturing | $103,000 | $103,468 | 18 | <$5M | Research |
| Parks Family Dentistry, P.c. | Health Care and Social Assistance | $90,300 | $91,257 | 9 | <$5M | Research |
| Parks Family Dental PC | Health Care and Social Assistance | $84,862 | $85,741 | 10 | <$5M | Research |
| Blessing Gravel LLC | Mining, Quarrying, and Oil and Gas Extraction | $74,000 | $74,705 | 6 | <$5M | Research |
| Rjrx LLC | Retail Trade | $65,245 | $65,716 | 5 | <$5M | Research |
| Brad Lawley Properties LLC | Retail Trade | $62,400 | $63,045 | 16 | <$5M | Research |
| Tish Lumber Company, INC | Retail Trade | $56,230 | $56,529 | 10 | <$5M | Research |
| Noble Signs INC | Administrative and Support and Waste Management | $55,288 | $55,612 | 3 | <$5M | Research |
| Noble Signs INC | Agriculture, Forestry, Fishing and Hunting | $55,287 | $55,545 | 3 | <$5M | Research |
| Refuge Behavioral Health Pllc | Health Care and Social Assistance | $49,200 | $49,711 | 13 | <$5M | Research |
| Chaney's Simple Simon's Pizza LLC | Accommodation and Food Services | $47,500 | $47,819 | 41 | $7.3M | Research |
| Daniel Harcrow, LLC | Other Services (except Public Administration) | $40,100 | $40,491 | 7 | <$5M | Research |
| Real Screen Video LLC | Other Services (except Public Administration) | $39,700 | $39,957 | 4 | <$5M | Research |