| Harney County Health District | Retail Trade | $2,999,350 | $3,034,685 | 196 | N/A |  Research |
| Symmetry Care, Inc. | Other Services (except Public Administration) | $602,300 | $605,897 | 46 | N/A | Research |
| Harney Rock Paving & Co. | Construction | $481,920 | $483,742 | 44 | $13.6M | Research |
| Harney Rock Paving & Co. | Construction | $476,900 | $480,075 | 44 | $13.6M | Research |
| Harney County Senior and Community Services Center | Health Care and Social Assistance | $398,100 | $143,389 | 20 | N/A | Research |
| Burns Garage Inc. | Retail Trade | $270,525 | $272,786 | 19 | <$5M | Research |
| Burns Garage INC | Retail Trade | $270,247 | $272,557 | 26 | $6.6M | Research |
| Robbins Equipment - Burns, Inc. | Wholesale Trade | $214,300 | $215,533 | 25 | $7.7M | Research |
| Nora Corportion | Administrative and Support and Waste Management | $157,390 | $158,472 | 17 | <$5M | Research |
| Harney County Senior and Community Services Center | Health Care and Social Assistance | $143,391 | $143,980 | 22 | N/A | Research |
| Oster Professional Group Cpa's PC | Professional, Scientific, and Technical Services | $130,747 | $131,173 | 9 | <$5M | Research |
| Dh Ventures, LLC | Manufacturing | $124,695 | $127,076 | 43 | $42.6M | Research |
| Oster Professional Group, Cpa's, PC | Professional, Scientific, and Technical Services | $117,412 | $118,335 | 8 | <$5M | Research |
| Crane Hot Springs LLC | Accommodation and Food Services | $95,574 | $96,009 | 20 | $6.3M | Research |
| Burns Dental Group, LLC | Health Care and Social Assistance | $89,500 | $90,451 | 16 | <$5M | Research |
| Jefferson Foods Inc. | Retail Trade | $87,180 | $366,894 | 22 | $5.5M | Research |
| Reid's Pine Room LLC | Accommodation and Food Services | $81,931 | $82,550 | 14 | <$5M | Research |
| High Desert Partnership | Other Services (except Public Administration) | $76,437 | $76,837 | 7 | N/A | Research |
| Country Natural Beef Marketing, LLC | Agriculture, Forestry, Fishing and Hunting | $75,000 | $76,052 | 3 | <$5M | Research |
| County of Harney | Public Administration | $71,235 | $59,080 | 10 | N/A | Research |
| Crane Hot Springs LLC | Construction | $69,565 | $70,093 | 18 | $5.6M | Research |
| Tod's Auto Parts LLC | Retail Trade | $65,616 | $66,238 | 9 | <$5M | Research |
| Hotchkiss Company, Inc. | Agriculture, Forestry, Fishing and Hunting | $64,372 | $64,839 | 9 | <$5M | Research |
| Reid's Pine Room LLC | Accommodation and Food Services | $57,300 | $57,831 | 14 | <$5M | Research |
| Kool Canadian Kids, LLC | Accommodation and Food Services | $51,500 | $51,995 | 17 | <$5M | Research |