| North Bend Medical Center, Inc. | Health Care and Social Assistance | $5,267,590 | $5,337,295 | 422 | $132.5M |  Research |
| Cardinal Services Inc. | Administrative and Support and Waste Management | $4,460,010 | $4,544,689 | 500 | $78.7M | Research |
| K. E. Mckay's Market of Coos Bay, Inc. | Retail Trade | $2,540,200 | $2,576,876 | 349 | $87.1M | Research |
| Cardinal Employers Organization, Inc. | Administrative and Support and Waste Management | $1,498,300 | $1,519,194 | 348 | $54.8M | Research |
| Bay Clinic, LLP | Health Care and Social Assistance | $1,356,000 | $1,366,328 | 105 | $33.0M | Research |
| Oregon Coast Community Action | Health Care and Social Assistance | $1,096,700 | $1,104,722 | 224 | N/A | Research |
| Docs Management Services LLC | Other Services (except Public Administration) | $936,558 | $945,872 | 57 | $10.9M | Research |
| West Coast Contractors INC | Construction | $837,718 | $845,016 | 35 | $39.9M | Research |
| West Coast Contractors, Inc. | Construction | $771,100 | $777,396 | 66 | $20.5M | Research |
| Billeter Marine LLC | Construction | $630,833 | $637,677 | 40 | $12.4M | Research |
| Hawthorne Enterprises, INC | Retail Trade | $626,325 | $632,760 | 42 | $10.6M | Research |
| South Coast Orthopaedic Associates, PC | Health Care and Social Assistance | $616,246 | $623,016 | 30 | $6.0M | Research |
| Preferred Employer Solutions, LLC | Administrative and Support and Waste Management | $591,300 | $599,805 | 60 | $9.4M | Research |
| Chuck Bracelin Trucking, Inc. | Transportation and Warehousing | $562,400 | $1,610,638 | 145 | $21.9M | Research |
| South Coast Hospice & Palliative Care Services INC | Health Care and Social Assistance | $530,773 | $537,361 | 49 | N/A | Research |
| The Dyer Partnership, Engineers & Planners, INC | Professional, Scientific, and Technical Services | $454,000 | $456,550 | 26 | <$5M | Research |
| Jerry D. Bowers Trucking LLC | Transportation and Warehousing | $452,000 | $454,848 | 43 | $6.5M | Research |
| Spoony Bay Llc, DBA Mcdonald's | Accommodation and Food Services | $449,000 | $453,109 | 103 | $18.3M | Research |
| South Coast Dental Group | Health Care and Social Assistance | $438,112 | $490,822 | 40 | $9.3M | Research |
| Koos Transporation LLC | Transportation and Warehousing | $409,217 | $414,565 | 42 | $8.5M | Research |
| Koos Transportation LLC | Transportation and Warehousing | $409,215 | $415,011 | 34 | $9.1M | Research |
| Bowers Construction LLC | Transportation and Warehousing | $380,900 | $383,467 | 34 | $6.9M | Research |
| Gibs Rvs INC | Retail Trade | $371,200 | $373,498 | 29 | $7.6M | Research |
| Tower Motor Company | Retail Trade | $368,400 | $370,439 | 41 | $6.4M | Research |
| Jgs Precision Tool Mfg LLC | Manufacturing | $358,232 | $362,530 | 29 | $7.6M | Research |