| Coquille Valley Hospital District | Health Care and Social Assistance | $3,562,900 | $3,603,605 | 226 | N/A | Research |
| Lba Contract Cutting Inc. | Agriculture, Forestry, Fishing and Hunting | $537,630 | $542,454 | 38 | <$5M | Research |
| Tony Holman Logging, LLC | Agriculture, Forestry, Fishing and Hunting | $474,400 | $479,417 | 45 | <$5M | Research |
| La Logging, INC | Agriculture, Forestry, Fishing and Hunting | $339,500 | $341,453 | 26 | <$5M | Research |
| Charlie Yates Ranching INC | Mining, Quarrying, and Oil and Gas Extraction | $311,010 | $313,248 | 24 | <$5M | Research |
| Charlie Yates Ranching INC | Wholesale Trade | $309,670 | $313,042 | 26 | $8.0M | Research |
| Blaylock Inc. | Agriculture, Forestry, Fishing and Hunting | $287,600 | $289,594 | 23 | <$5M | Research |
| Danish Dairy LLC | Manufacturing | $178,300 | $179,240 | 18 | $6.4M | Research |
| Pahls Dentistry PC | Health Care and Social Assistance | $171,112 | $171,989 | 17 | <$5M | Research |
| Wyatt Timber LLC | Agriculture, Forestry, Fishing and Hunting | $163,600 | $165,335 | 11 | <$5M | Research |
| Doug Backman Construction, Inc. | Wholesale Trade | $143,300 | $144,898 | 25 | $7.7M | Research |
| Myrtle Veterinary Hospital Business LLC | Professional, Scientific, and Technical Services | $127,000 | $128,336 | 14 | <$5M | Research |
| Morrison Gederos LLC | Construction | $125,833 | $126,240 | 19 | $5.8M | Research |
| Coquille Pizza Company LLC | Accommodation and Food Services | $121,700 | $122,817 | 13 | <$5M | Research |
| Morrison Gederos LLC | Construction | $107,600 | $108,585 | 21 | $6.4M | Research |
| Zb Contract Cutting LLC | Agriculture, Forestry, Fishing and Hunting | $104,500 | $105,528 | 10 | <$5M | Research |
| Green Mountain Chipping, Inc. | Agriculture, Forestry, Fishing and Hunting | $98,600 | $99,586 | 7 | <$5M | Research |
| Four Mile Logging, Inc. | Agriculture, Forestry, Fishing and Hunting | $95,400 | $96,370 | 9 | <$5M | Research |
| Hemr Industrial Contractors LLC | Construction | $89,865 | $90,850 | 12 | $13.7M | Research |
| Gb Construction Co. | Construction | $84,500 | $0 | 8 | <$5M | Research |
| Jimmy Hill Jr Trucking LLC | Transportation and Warehousing | $80,000 | $80,885 | 5 | <$5M | Research |
| B & D Trucking LLC | Transportation and Warehousing | $77,500 | $78,315 | 6 | <$5M | Research |
| Coquille Automotive LLC | Other Services (except Public Administration) | $64,700 | $50,460 | 6 | <$5M | Research |
| Fraziers Bakery & Restaurant | Accommodation and Food Services | $61,180 | $61,478 | 12 | <$5M | Research |
| Fraziers Bakery & Restaurant | Accommodation and Food Services | $60,000 | $60,727 | 14 | <$5M | Research |