| Confederated Tribes of the Coos Lower Umpqua Siuslaw Indians | Arts, Entertainment, and Recreation | $3,402,100 | $3,177,876 | 374 | $52.4M | Research |
| R & R King Logging, Inc. | Agriculture, Forestry, Fishing and Hunting | $691,500 | $699,211 | 5 | <$5M | Research |
| Regency Florence, LLC | Health Care and Social Assistance | $634,800 | $641,589 | 74 | $12.6M | Research |
| R & R King Logging INC | Agriculture, Forestry, Fishing and Hunting | $587,585 | $591,384 | 50 | $5.1M | Research |
| Confederated Tribes of the Coos Lower Umpqua Siuslaw Indians | Arts, Entertainment, and Recreation | $557,700 | $561,016 | 71 | $9.9M | Research |
| Spruce Point INC | Health Care and Social Assistance | $397,100 | $401,985 | 66 | $11.2M | Research |
| Gary Foglio Trucking, Inc. | Agriculture, Forestry, Fishing and Hunting | $354,900 | $356,922 | 31 | <$5M | Research |
| Hoagland Properties INC | Accommodation and Food Services | $336,949 | $339,829 | 43 | $13.4M | Research |
| The Bridgewater Restaurant INC | Accommodation and Food Services | $320,138 | $322,699 | 34 | $6.0M | Research |
| Driftwood Shores Rental Pool LLC | Accommodation and Food Services | $298,155 | $299,813 | 35 | $10.9M | Research |
| Florence Coastal Hardware INC | Retail Trade | $268,225 | $271,738 | 18 | <$5M | Research |
| The Bridgewater Restaurant Inc. | Accommodation and Food Services | $231,100 | $233,037 | 34 | $6.0M | Research |
| Florence Dental Clinic INC | Health Care and Social Assistance | $211,700 | $212,790 | 19 | <$5M | Research |
| Hoagland Properties, INC | Accommodation and Food Services | $208,600 | $210,675 | 43 | $13.4M | Research |
| Elderberry Square Community, LLC | Health Care and Social Assistance | $207,900 | $208,977 | 43 | $7.3M | Research |
| Rye Tree Service INC | Administrative and Support and Waste Management | $203,100 | $204,597 | 35 | $7.6M | Research |
| Johnston Motor Company | Retail Trade | $200,000 | $201,299 | 18 | <$5M | Research |
| Johnston Motor Company | Retail Trade | $199,903 | $201,162 | 18 | <$5M | Research |
| Reinard Pollmann | Accommodation and Food Services | $195,351 | $197,021 | 44 | $13.8M | Research |
| Driftwood Shores Rental Pool LLC | Accommodation and Food Services | $185,500 | $186,786 | 145 | $45.3M | Research |
| B-W Pier Point Inn LLC | Accommodation and Food Services | $182,763 | $184,002 | 30 | $9.4M | Research |
| Sea Lion Caves INC | Arts, Entertainment, and Recreation | $182,056 | $183,223 | 21 | <$5M | Research |
| Sea Lion Caves INC | Arts, Entertainment, and Recreation | $182,056 | $183,188 | 14 | <$5M | Research |
| Duman INC | Construction | $169,700 | $171,160 | 12 | <$5M | Research |
| Costa Acquisition, Inc. | Retail Trade | $160,900 | $162,029 | 16 | <$5M | Research |