| Lapine Community Health Center | Other Services (except Public Administration) | $903,732 | $910,368 | 74 | N/A |  Research |
| Scott Logging INC | Agriculture, Forestry, Fishing and Hunting | $310,155 | $312,317 | 33 | <$5M | Research |
| Scott Logging INC | Agriculture, Forestry, Fishing and Hunting | $260,804 | $263,166 | 22 | <$5M | Research |
| La Pine Travel Center LLC | Retail Trade | $242,657 | $244,007 | 38 | $12.7M | Research |
| Vic Russell Construction, Inc. | Construction | $223,695 | $225,846 | 32 | $9.9M | Research |
| Drug Mart Pharmacy INC | Retail Trade | $155,200 | $157,113 | 16 | <$5M | Research |
| La Pine Animal Hospital INC | Professional, Scientific, and Technical Services | $145,958 | $147,026 | 13 | <$5M | Research |
| Triton Polling & Research Inc. | Professional, Scientific, and Technical Services | $139,172 | $96,970 | 20 | <$5M | Research |
| Triton Polling & Research, INC | Professional, Scientific, and Technical Services | $139,172 | $140,722 | 25 | <$5M | Research |
| Stephen W. Allen P.c. | Health Care and Social Assistance | $126,777 | $114,918 | 9 | <$5M | Research |
| Little River Investments INC | Finance and Insurance | $125,278 | $126,130 | 12 | $6.2M | Research |
| La Pine Travel Center LLC | Retail Trade | $119,570 | $120,473 | 52 | $17.4M | Research |
| Stephen W. Allen P.c. | Health Care and Social Assistance | $114,305 | $114,815 | 12 | <$5M | Research |
| Wickiup Rose INC | Agriculture, Forestry, Fishing and Hunting | $108,290 | $109,141 | 19 | <$5M | Research |
| La Pine Auto Supply | Retail Trade | $104,469 | $105,042 | 13 | <$5M | Research |
| Northwest Dental Group Pc-Lapine | Health Care and Social Assistance | $102,394 | $103,239 | 9 | <$5M | Research |
| Northwest Dental Group P.c. Lapine | Health Care and Social Assistance | $102,394 | $102,961 | 9 | <$5M | Research |
| Christopher Evan Bright | Unknown | $100,000 | $16,907 | 1 | N/A | Research |
| Perry Walters Construction Inc. | Construction | $97,035 | $97,665 | 12 | $13.7M | Research |
| Perry Walters Construction INC | Construction | $88,742 | $89,391 | 10 | $11.4M | Research |
| Juniper Biolabs INC | Unknown | $83,362 | $0 | 8 | N/A | Research |
| Dsplumbing LLC | Construction | $80,000 | $6,951 | 4 | <$5M | Research |
| Cassidy Bayou Partners II LLC | Accommodation and Food Services | $77,655 | $109,439 | 10 | <$5M | Research |
| Seasonal Marketing Inc. | Wholesale Trade | $73,860 | $74,392 | 6 | <$5M | Research |
| Blue Duck LLC | Accommodation and Food Services | $72,600 | $73,336 | 10 | <$5M | Research |