| Keith Manufacturing Company | Wholesale Trade | $2,752,342 | $2,786,440 | 216 | $66.2M |  Research |
| Warm Springs Casino Enterprises | Arts, Entertainment, and Recreation | $1,766,407 | $1,774,199 | 185 | N/A | Research |
| Central Oregon Seeds, Inc. | Agriculture, Forestry, Fishing and Hunting | $815,273 | $823,652 | 85 | <$5M | Research |
| East Cascade Retirement Community, LLC | Health Care and Social Assistance | $464,800 | $467,181 | 86 | $14.6M | Research |
| Madras Medical Group, PC | Health Care and Social Assistance | $426,610 | $432,022 | 26 | <$5M | Research |
| Black Bear Diner of Madras LLC | Accommodation and Food Services | $265,114 | $268,019 | 42 | $7.5M | Research |
| Gary Gruner Motor Co | Retail Trade | $255,365 | $258,226 | 18 | <$5M | Research |
| Madras Farms Co. | Agriculture, Forestry, Fishing and Hunting | $252,826 | $256,199 | 48 | <$5M | Research |
| Madras Farms Co. | Agriculture, Forestry, Fishing and Hunting | $239,935 | $244,116 | 18 | <$5M | Research |
| Shielding International INC | Manufacturing | $208,087 | $209,428 | 25 | $8.8M | Research |
| Owanjay Services, Inc. | Administrative and Support and Waste Management | $206,515 | $208,405 | 22 | <$5M | Research |
| Black Bear Diner of Madras LLC | Accommodation and Food Services | $198,564 | $201,088 | 50 | $8.9M | Research |
| Boyle Family Farms LLC | Agriculture, Forestry, Fishing and Hunting | $194,139 | $150,508 | 10 | <$5M | Research |
| Ts&s Auto, Inc. | Retail Trade | $189,859 | $192,301 | 17 | <$5M | Research |
| Shielding International INC | Manufacturing | $181,835 | $182,951 | 18 | $5.0M | Research |
| Rawhide Excavating Inc. | Construction | $180,750 | $181,327 | 15 | <$5M | Research |
| High Desert Organix LLC | Manufacturing | $149,640 | $150,435 | 8 | $7.9M | Research |
| High Desert Organix, LLC | Manufacturing | $149,640 | $151,057 | 10 | $9.9M | Research |
| Shree Narayan Management Inc. | Accommodation and Food Services | $144,565 | $145,529 | 22 | $6.9M | Research |
| Boyle Family Farms LLC | Agriculture, Forestry, Fishing and Hunting | $143,642 | $144,362 | 10 | <$5M | Research |
| Norton Cattle Company LLC | Agriculture, Forestry, Fishing and Hunting | $143,525 | $144,693 | 10 | <$5M | Research |
| Quality Sounds INC | Retail Trade | $139,973 | $141,350 | 29 | $7.8M | Research |
| Rory & Ryan II LLC | Accommodation and Food Services | $139,454 | $140,391 | 11 | <$5M | Research |
| Baggett Inc. | Construction | $136,425 | $137,641 | 17 | $6.4M | Research |
| Shanti Management LLC | Accommodation and Food Services | $129,027 | $129,887 | 19 | $5.9M | Research |