| Mike Dorazio INC | Other Services (except Public Administration) | $163,000 | $159,453 | 11 | <$5M | AI Deep Dive |
| Mark C. Spicher | Wholesale Trade | $162,500 | $163,416 | 17 | <$5M | AI Deep Dive |
| Heavy Duty Tire and Treads, Inc. | Retail Trade | $157,600 | $125,619 | 18 | <$5M | AI Deep Dive |
| Capital Resource Conservation and Development Area Council I | Professional, Scientific, and Technical Services | $157,500 | $26,653 | 24 | N/A | AI Deep Dive |
| J Herman Bosler Memorial Library | Information | $157,440 | $159,101 | 37 | N/A | AI Deep Dive |
| Carlisle Day Care Center | Health Care and Social Assistance | $157,412 | $159,064 | 35 | N/A | AI Deep Dive |
| J. Herman Bosler Memorial Library (bosler Free Library) | Information | $157,400 | $159,207 | 40 | N/A | AI Deep Dive |
| Mike Dorazio INC | Other Services (except Public Administration) | $157,400 | $159,259 | 14 | <$5M | AI Deep Dive |
| Torres Credit Services, Inc. | Administrative and Support and Waste Management | $156,307 | $158,000 | 20 | <$5M | AI Deep Dive |
| Carlisle Pubs, INC | Accommodation and Food Services | $156,208 | $158,186 | 13 | <$5M | AI Deep Dive |
| David Hartzell | Health Care and Social Assistance | $155,840 | $158,304 | 11 | <$5M | AI Deep Dive |
| Romeo and Juliet INC | Accommodation and Food Services | $155,835 | $157,620 | 50 | $8.9M | AI Deep Dive |
| Hartzell Eye Specialists LLC | Health Care and Social Assistance | $155,800 | $157,939 | 4 | <$5M | AI Deep Dive |
| Z-Band Technologies, LLC | Manufacturing | $155,000 | $156,145 | 16 | <$5M | AI Deep Dive |
| Gingerbread Man of Carlisle, Inc. | Accommodation and Food Services | $153,400 | $155,602 | 32 | $5.7M | AI Deep Dive |
| Scalles, Inc. | Accommodation and Food Services | $152,025 | $153,056 | 37 | $6.6M | AI Deep Dive |
| Molly Pitcher Brewing Co | Manufacturing | $151,800 | $153,746 | 19 | $6.7M | AI Deep Dive |
| Flenniken & Flenniken PC | Health Care and Social Assistance | $151,667 | $153,034 | 16 | <$5M | AI Deep Dive |
| George Ely Associates, Inc. | Manufacturing | $151,200 | $152,219 | 8 | <$5M | AI Deep Dive |
| Shree Krishna Hospitality LP | Accommodation and Food Services | $151,008 | $151,765 | 11 | <$5M | AI Deep Dive |
| Thomas P Neslund Dmd PC | Health Care and Social Assistance | $150,500 | $152,047 | 22 | $5.1M | AI Deep Dive |
| Thomas P Neslund Dmd, PC | Health Care and Social Assistance | $150,500 | $152,293 | 10 | <$5M | AI Deep Dive |
| We Rock 160, LLC | Accommodation and Food Services | $150,200 | $151,234 | 24 | <$5M | AI Deep Dive |
| George Ely Associates INC | Manufacturing | $150,000 | $151,747 | 8 | <$5M | AI Deep Dive |
| Phantom Communication Systems INC | Arts, Entertainment, and Recreation | $149,985 | $150,963 | 10 | <$5M | AI Deep Dive |