| Restoration Relief, INC | Construction | $351,000 | $354,154 | 34 | $10.3M |  Research |
| Zimmerman Excavating of Ephrata, Inc. | Construction | $337,877 | $341,537 | 14 | $5.2M | Research |
| Ephrata Church of the Nazarene | Other Services (except Public Administration) | $336,572 | $339,788 | 63 | N/A | Research |
| John D Sauder Auto Company INC | Retail Trade | $334,115 | $336,861 | 32 | $7.6M | Research |
| Terkins INC | Construction | $324,665 | $327,307 | 22 | $7.2M | Research |
| Teamag, Inc. | Professional, Scientific, and Technical Services | $316,400 | $318,914 | 26 | <$5M | Research |
| Midline Mechanical Llc. | Construction | $309,921 | $312,272 | 25 | $28.5M | Research |
| Stump's Decks & Porches Llc. | Construction | $307,930 | $311,215 | 29 | $6.7M | Research |
| Stumps Decks and Porches LLC | Construction | $306,527 | $301,850 | 26 | $8.2M | Research |
| Weaver Nut Company INC | Wholesale Trade | $303,200 | $307,221 | 29 | $7.5M | Research |
| R&r Pole Buildings | Construction | $299,980 | $151,775 | 13 | <$5M | Research |
| Double Run Carriers Inc. | Transportation and Warehousing | $295,815 | $297,401 | 16 | <$5M | Research |
| Ephrata Mennonite School | Educational Services | $295,305 | $296,929 | 62 | N/A | Research |
| Hinkletown Mennonite School | Educational Services | $290,250 | $291,826 | 50 | N/A | Research |
| Mem Associates LLC | Manufacturing | $286,715 | $289,415 | 20 | $19.8M | Research |
| Dynamic Growth Dental Support LLC | Health Care and Social Assistance | $283,032 | $286,545 | 133 | $30.8M | Research |
| Scopos Hospitality Group LLC | Professional, Scientific, and Technical Services | $279,900 | $262,983 | 24 | $7.4M | Research |
| Ephrata Mennonite School | Educational Services | $273,629 | $275,164 | 62 | N/A | Research |
| Scopos Hospitality Group LLC | Professional, Scientific, and Technical Services | $268,587 | $272,616 | 21 | <$5M | Research |
| Aligned Dental of Lancaster, PC | Health Care and Social Assistance | $256,900 | $260,285 | 23 | $5.3M | Research |
| Zimmerman Group INC | Transportation and Warehousing | $254,300 | $257,655 | 18 | <$5M | Research |
| Aligned Dental of Lancaster PC | Health Care and Social Assistance | $243,614 | $246,744 | 133 | $30.8M | Research |
| Mccarty & Son INC | Wholesale Trade | $238,414 | $239,739 | 13 | <$5M | Research |
| Brenneman Printing Inc. | Manufacturing | $237,090 | $239,571 | 19 | $5.3M | Research |
| Ephrata Recreation Center | Arts, Entertainment, and Recreation | $236,380 | $239,046 | 64 | N/A | Research |