| U-Gro Learning Centres, Inc. | Educational Services | $2,481,500 | $2,509,486 | 389 | $51.9M |  Research |
| Prescient Medicine Holdings, Inc. | Manufacturing | $1,542,000 | $1,552,237 | 103 | $102.2M | Research |
| Central Pennsylvania Blood Bank | Health Care and Social Assistance | $924,000 | $930,288 | 99 | N/A | Research |
| Pacific Edge Diagnostics USA Ltd | Health Care and Social Assistance | $530,243 | $533,264 | 29 | $6.7M | Research |
| B&w, Inc. | Construction | $405,800 | $408,470 | 28 | $8.9M | Research |
| Leidich Enterprises, Inc. | Transportation and Warehousing | $334,100 | $337,935 | 26 | <$5M | Research |
| 550 East Main LLC | Accommodation and Food Services | $328,909 | $332,682 | 12 | <$5M | Research |
| Grace United Methodist Church-Hummelstown | Other Services (except Public Administration) | $275,300 | $277,276 | 51 | N/A | Research |
| Grace United Methodist Church-Hummelstown | Other Services (except Public Administration) | $274,887 | $276,371 | 48 | N/A | Research |
| Jld Property Management Group INC | Administrative and Support and Waste Management | $257,607 | $0 | 18 | <$5M | Research |
| Shahane T. Kirman Od & Associates | Manufacturing | $251,375 | $252,872 | 17 | <$5M | Research |
| Hershey Dental Associates LLC | Health Care and Social Assistance | $248,922 | $251,527 | 39 | $9.0M | Research |
| Hershey Dental Associates, LLC | Health Care and Social Assistance | $240,707 | $243,734 | 26 | $6.0M | Research |
| Hummelstown Fuel Oil Svc. INC | Construction | $238,000 | $239,349 | 16 | $5.1M | Research |
| 550 East Main LLC | Accommodation and Food Services | $234,900 | $238,221 | 38 | $11.9M | Research |
| Hummelstown Fuel Oil Svc. Inc. | Retail Trade | $227,022 | $228,135 | 15 | <$5M | Research |
| Wm Reinhold, Inc. | Administrative and Support and Waste Management | $226,400 | $228,815 | 23 | <$5M | Research |
| All Nk Hershey LLC | Accommodation and Food Services | $224,447 | $227,857 | 25 | $7.8M | Research |
| Coreintegrator, LLC | Professional, Scientific, and Technical Services | $220,300 | $221,542 | 12 | <$5M | Research |
| Mt Construction Inc. | Construction | $218,204 | $220,113 | 28 | $9.5M | Research |
| Mt Weatherization, Inc. | Construction | $215,600 | $217,840 | 23 | $7.8M | Research |
| Woodward & Associates PC | Health Care and Social Assistance | $210,000 | $211,103 | 14 | <$5M | Research |
| Tnt Food Enterprises LLC | Accommodation and Food Services | $192,703 | $194,084 | 16 | <$5M | Research |
| Prismworks Technology INC | Professional, Scientific, and Technical Services | $179,405 | $181,420 | 10 | <$5M | Research |
| Prismworks Technology, Inc. | Professional, Scientific, and Technical Services | $179,400 | $180,707 | 9 | <$5M | Research |