| Public Health Management Corporation | Public Administration | $10,000,000 | $10,079,444 | 441 | N/A |  Research |
| J.j. White, Inc. | Construction | $10,000,000 | $10,112,877 | 500 | $155.0M | Research |
| The Philadelphia Inquirer LLC | Information | $10,000,000 | $10,076,986 | 500 | $84.0M | Research |
| Nelson Worldwide, LLC | Professional, Scientific, and Technical Services | $10,000,000 | $10,114,333 | 500 | $155.0M | Research |
| Penn Power Group, LLC | Wholesale Trade | $9,281,800 | $9,388,350 | 500 | $153.2M | Research |
| Mccormick Taylor, Inc. | Professional, Scientific, and Technical Services | $8,844,000 | $8,977,993 | 414 | $51.1M | Research |
| Cardiology Consultants of Philadelphia, PC | Health Care and Social Assistance | $8,332,615 | $8,427,584 | 500 | $156.9M | Research |
| Ewing Cole INC | Professional, Scientific, and Technical Services | $8,206,300 | $4,061,730 | 462 | $143.2M | Research |
| White and Williams LLP | Professional, Scientific, and Technical Services | $7,240,000 | $7,322,119 | 404 | $98.2M | Research |
| City of Phila Acting by the Brd of Dir of City Trusts | Health Care and Social Assistance | $6,960,300 | $7,050,204 | 418 | $82.9M | Research |
| Herman Goldner Company, Inc. | Construction | $6,688,075 | $6,763,934 | 349 | $110.4M | Research |
| American College of Physicians, INC | Educational Services | $6,416,510 | $6,502,776 | 309 | $37.1M | Research |
| Penn Jersey Paper Co. | Wholesale Trade | $6,393,800 | $6,472,124 | 464 | $119.4M | Research |
| Pei Genesis, Inc. | Manufacturing | $6,274,300 | $6,351,998 | 500 | $130.9M | Research |
| James D. Morrissey, Inc. | Construction | $6,189,947 | $6,261,992 | 182 | $56.4M | Research |
| Greater Philadelphia Health Action Incorporated | Health Care and Social Assistance | $6,000,000 | $6,074,630 | 486 | N/A | Research |
| Urban Engineers, Inc. Employee Stock Ownership Plan | Professional, Scientific, and Technical Services | $5,936,552 | $6,022,103 | 377 | $46.5M | Research |
| James J Anderson Construction Company INC | Construction | $5,750,713 | $5,830,593 | 270 | $83.7M | Research |
| Campus Apartments LLC | Real Estate and Rental and Leasing | $5,688,307 | $5,311,995 | 431 | $64.7M | Research |
| Zentis North America, LLC | Manufacturing | $5,662,800 | $5,726,099 | 350 | $123.5M | Research |
| North Philadelphia Health Systems | Health Care and Social Assistance | $5,444,600 | $4,805,697 | 314 | $62.3M | Research |
| Mastery Schools of Camden Inc. | Unknown | $5,252,870 | $5,315,185 | 320 | N/A | Research |
| Samuels and Son Seafood Co Inc. | Wholesale Trade | $5,184,900 | $5,260,657 | 439 | $113.0M | Research |
| Pennrose Management Company | Real Estate and Rental and Leasing | $5,131,282 | $5,195,993 | 1 | <$5M | Research |
| Philadelphia Museum of Art | Arts, Entertainment, and Recreation | $5,099,447 | $5,158,265 | 479 | $72.8M | Research |