| Emergency Care Research Institute | Health Care and Social Assistance | $8,869,450 | $8,969,970 | 462 | N/A |  Research |
| Philadelphia D & M, Inc. | Construction | $7,084,400 | $7,165,477 | 409 | $139.4M | Research |
| United Anesthesia Services PC | Health Care and Social Assistance | $6,526,600 | $6,603,469 | 365 | $114.6M | Research |
| Retinovitreous Associates Ltd | Health Care and Social Assistance | $3,444,000 | $3,483,630 | 360 | $113.0M | Research |
| Ave Management LLC | Real Estate and Rental and Leasing | $3,283,467 | $3,328,176 | 281 | $42.1M | Research |
| Premier Dental Products Company | Manufacturing | $3,147,000 | $2,081,258 | 158 | $44.1M | Research |
| Crompco LLC | Professional, Scientific, and Technical Services | $2,826,200 | $3,057,617 | 236 | $47.6M | Research |
| Spray Products Corporation | Manufacturing | $2,618,045 | $2,656,370 | 187 | $185.5M | Research |
| Malvern Institute for Psychiatric & Alcoholic Studies | Health Care and Social Assistance | $2,293,570 | $2,323,292 | 261 | $51.8M | Research |
| Griswold International LLC | Health Care and Social Assistance | $2,175,257 | $2,198,261 | 500 | $85.6M | Research |
| Progressions Behavioral Health Services, INC | Health Care and Social Assistance | $1,882,249 | $1,918,708 | 300 | $53.4M | Research |
| United Food & Commercial Workers Local 1776 | Other Services (except Public Administration) | $1,669,762 | $1,674,840 | 82 | $15.7M | Research |
| Forty Two LLC | Real Estate and Rental and Leasing | $1,390,100 | $1,401,028 | 117 | $21.4M | Research |
| Markel Corporation | Manufacturing | $1,192,200 | $682,358 | 81 | $19.8M | Research |
| Suburban Geriatrics INC a Professional C | Unknown | $1,146,334 | $1,159,776 | 61 | N/A | Research |
| Synergy Orthopedics, LLC | Health Care and Social Assistance | $1,144,755 | $1,159,621 | 80 | $13.7M | Research |
| Synergy Orthopedics LLC | Health Care and Social Assistance | $1,138,760 | $1,153,798 | 87 | $14.9M | Research |
| Braeburn Inc. | Manufacturing | $1,108,097 | $1,119,573 | 30 | $29.8M | Research |
| O'brien & Ryan LLP Attorneys at Law | Professional, Scientific, and Technical Services | $1,015,123 | $1,030,029 | 65 | $15.8M | Research |
| American Exploration Company | Transportation and Warehousing | $891,700 | $911,070 | 70 | $10.6M | Research |
| Dawkins Management Group, LLC | Accommodation and Food Services | $850,660 | $861,789 | 367 | $65.2M | Research |
| The Apella Group LLC | Information | $819,262 | $825,235 | 43 | $7.2M | Research |
| Riley Sales, Inc. | Wholesale Trade | $769,300 | $776,656 | 64 | $19.6M | Research |
| Riley Sales Inc. | Wholesale Trade | $769,300 | $774,169 | 64 | $19.6M | Research |
| The Bailey Group INC | Professional, Scientific, and Technical Services | $768,900 | $738,287 | 30 | $7.0M | Research |