| Empire Group of Reading PA INC | Administrative and Support and Waste Management | $10,000,000 | $2,558,636 | 162 | $30.6M |  Research |
| Brentwood Industries INC | Manufacturing | $8,091,300 | $8,202,106 | 500 | $495.9M | Research |
| Sweet Street Desserts INC | Manufacturing | $7,420,600 | $7,504,682 | 500 | $176.5M | Research |
| Supportive Concepts for Families Inc. | Health Care and Social Assistance | $7,111,120 | $7,167,230 | 500 | $85.1M | Research |
| Stevens & Lee, P.c. | Professional, Scientific, and Technical Services | $6,422,467 | $6,496,193 | 270 | $65.6M | Research |
| Pollock Research & Design, Inc. | Manufacturing | $5,720,271 | $5,787,504 | 306 | $80.1M | Research |
| Alvernia University | Public Administration | $5,302,315 | $5,990,306 | 395 | N/A | Research |
| Elite Sportswear, L.p. | Manufacturing | $5,249,200 | $5,309,274 | 500 | $176.5M | Research |
| R. M. Palmer Company | Manufacturing | $5,000,000 | $5,057,534 | 500 | $176.5M | Research |
| Albright College | Educational Services | $4,692,430 | $0 | 44 | N/A | Research |
| The Loomis Companies, Ltd. | Finance and Insurance | $3,969,141 | $4,016,118 | 389 | $199.9M | Research |
| Gage Enterprises, Inc. | Administrative and Support and Waste Management | $3,816,049 | $3,864,703 | 255 | $40.1M | Research |
| Herbein + Company, INC | Professional, Scientific, and Technical Services | $3,241,418 | $3,286,709 | 182 | $57.9M | Research |
| Weidenhammer Systems Corporation | Professional, Scientific, and Technical Services | $3,236,995 | $3,020,780 | 152 | $31.4M | Research |
| E4 Services LLC | Professional, Scientific, and Technical Services | $3,206,500 | $3,244,539 | 320 | $33.1M | Research |
| Prospectus Associates, Inc. | Health Care and Social Assistance | $3,201,500 | $3,047,671 | 324 | N/A | Research |
| Fidelity Technologies Corporation | Manufacturing | $3,200,000 | $3,232,978 | 458 | $119.9M | Research |
| Clover Farms Dairy Company | Agriculture, Forestry, Fishing and Hunting | $2,991,300 | $3,027,196 | 198 | $32.4M | Research |
| The Highlands at Wyomissing | Health Care and Social Assistance | $2,451,200 | $2,479,321 | 164 | $27.9M | Research |
| Fm Brown's Sons, Inc. | Manufacturing | $2,421,352 | $2,449,130 | 162 | $57.2M | Research |
| C H Briggs Company INC | Wholesale Trade | $2,408,000 | $2,380,135 | 167 | $51.2M | Research |
| Berks Packing Company INC | Manufacturing | $2,379,900 | $2,058,981 | 146 | $51.5M | Research |
| Select Grille, LLC | Accommodation and Food Services | $2,367,700 | $2,394,600 | 250 | $44.4M | Research |
| Standard Offset Printing Company | Manufacturing | $2,340,000 | $2,357,255 | 207 | $205.3M | Research |
| Ifs Industries, INC | Manufacturing | $2,228,700 | $2,249,949 | 167 | $165.6M | Research |