| Hranec Sheet Metal INC | Construction | $2,000,000 | $2,014,444 | 185 | $58.5M |  Research |
| Chestnut Ridge Counseling Services INC | Health Care and Social Assistance | $1,875,000 | $1,900,885 | 207 | N/A | Research |
| Mount Macrina Manor Nursing Home | Health Care and Social Assistance | $1,465,700 | $1,484,252 | 189 | N/A | Research |
| O. C. Cluss Lumber Company | Wholesale Trade | $1,421,700 | $1,437,378 | 50 | $15.3M | Research |
| George R Smalley Company INC | Construction | $1,104,224 | $1,113,487 | 79 | $26.0M | Research |
| Cherry Tree Healthcare Corp | Health Care and Social Assistance | $957,000 | $962,290 | 125 | $21.3M | Research |
| Lafayette Manor INC | Administrative and Support and Waste Management | $930,200 | $936,272 | 135 | N/A | Research |
| Black Diamond Rentals LLC | Real Estate and Rental and Leasing | $853,777 | $861,676 | 58 | $26.2M | Research |
| Tsitouch, Inc. | Manufacturing | $853,400 | $862,693 | 53 | $13.9M | Research |
| Tsitouch INC | Manufacturing | $834,777 | $840,806 | 51 | $13.4M | Research |
| Nikae Foods, Inc. | Retail Trade | $786,300 | $795,299 | 312 | $77.9M | Research |
| Fayette County Community Action Agency, Inc. | Public Administration | $774,400 | $782,499 | 65 | N/A | Research |
| Coolspring Stone Supply INC | Mining, Quarrying, and Oil and Gas Extraction | $678,000 | $683,123 | 64 | <$5M | Research |
| Tri Star Connellsville INC | Retail Trade | $612,465 | $617,063 | 270 | $68.0M | Research |
| Tri Star Connellsville INC | Retail Trade | $612,400 | $616,947 | 70 | $17.6M | Research |
| Coolspring Stone Supply Inc. | Mining, Quarrying, and Oil and Gas Extraction | $596,870 | $600,219 | 63 | <$5M | Research |
| Aaa Senior Care, LLC | Health Care and Social Assistance | $575,000 | $581,837 | 124 | $21.2M | Research |
| K2 Inc. | Professional, Scientific, and Technical Services | $547,400 | $551,096 | 26 | <$5M | Research |
| Engineering Ventures, PC | Professional, Scientific, and Technical Services | $546,660 | $553,325 | 32 | <$5M | Research |
| Craft Tire Inc. | Manufacturing | $543,022 | $545,548 | 52 | $51.6M | Research |
| Pine Hollow Mechanical, Inc. | Construction | $527,500 | $523,481 | 42 | $13.3M | Research |
| Southwestern Gastrointestinal Specialists, PC | Health Care and Social Assistance | $526,100 | $533,363 | 36 | $11.3M | Research |
| Laurel Business Institute | Educational Services | $520,365 | $524,239 | 73 | $15.3M | Research |
| Golden Eagle Construction Company | Construction | $519,194 | $522,973 | 69 | $21.4M | Research |
| Southwestern Gastrointestinal Specialists PC | Health Care and Social Assistance | $507,957 | $513,446 | 33 | $10.4M | Research |