| Eye Consultants of Pennsylvania, PC | Health Care and Social Assistance | $2,465,020 | $2,492,912 | 228 | $71.6M |  Research |
| Valley Forge Flag Company, Inc. | Manufacturing | $2,208,830 | $2,233,763 | 418 | $147.5M | Research |
| Eye Consultants of Pennsylvania PC | Health Care and Social Assistance | $2,000,000 | $2,012,712 | 253 | $79.4M | Research |
| Cjkantrg Management, LLC | Administrative and Support and Waste Management | $1,727,800 | $1,710,769 | 115 | $18.1M | Research |
| Tristar Products, Inc. | Wholesale Trade | $1,719,177 | $1,735,333 | 100 | $30.6M | Research |
| Amdent Ltd. | Management of Companies and Enterprises | $1,315,459 | $1,324,037 | 125 | $20.5M | Research |
| Keystone Orthopaedic Specialists | Health Care and Social Assistance | $1,176,500 | $1,190,291 | 97 | $30.4M | Research |
| Rpa Associates, Inc. | Professional, Scientific, and Technical Services | $1,132,100 | $1,138,613 | 52 | $10.5M | Research |
| Berks Schuylkill Respiratory Specialists | Health Care and Social Assistance | $1,087,290 | $1,098,918 | 93 | $29.2M | Research |
| Orthopaedic Associates of Reading, Ltd. | Health Care and Social Assistance | $1,029,124 | $1,036,985 | 69 | $21.7M | Research |
| Keystone Orthopaedic Specialists | Health Care and Social Assistance | $1,029,093 | $1,038,326 | 87 | $27.3M | Research |
| Orthopaedic Associates of Reading Ltd. | Professional, Scientific, and Technical Services | $1,024,890 | $1,032,471 | 83 | $11.6M | Research |
| Center for Urologic Care of Berks Co | Health Care and Social Assistance | $931,742 | $940,498 | 71 | $22.3M | Research |
| Kozloff Stoudt, P.c | Professional, Scientific, and Technical Services | $886,807 | $896,242 | 60 | $14.6M | Research |
| Kozloff Stoudt P.c. | Professional, Scientific, and Technical Services | $819,917 | $823,960 | 46 | $6.4M | Research |
| Berkshire Inn LP | Accommodation and Food Services | $719,827 | $721,898 | 79 | $24.7M | Research |
| Berkshire Psychiatric & Behavioral Health Services | Health Care and Social Assistance | $679,425 | $686,704 | 67 | $11.9M | Research |
| Russo Foods and Market, Inc. | Retail Trade | $671,925 | $675,496 | 59 | $6.6M | Research |
| Berks Plastic Surgery Institute, 7682 | Health Care and Social Assistance | $563,087 | $569,104 | 38 | $11.9M | Research |
| Carim Eye & Retina Center Ltd PC | Health Care and Social Assistance | $549,919 | $555,870 | 48 | $15.1M | Research |
| Wyomissing Dental Associates, P.c. | Health Care and Social Assistance | $539,600 | $546,740 | 39 | $9.0M | Research |
| Berks Oral Surgery Ltd. | Professional, Scientific, and Technical Services | $512,925 | $517,169 | 62 | $8.7M | Research |
| Wyomissing Dental Associates P.c. | Health Care and Social Assistance | $493,626 | $500,118 | 133 | $30.8M | Research |
| Constant Staffing LLC | Unknown | $480,755 | $484,483 | 307 | N/A | Research |
| Ent Head and Neck Specialists PC | Health Care and Social Assistance | $457,971 | $460,971 | 37 | $11.6M | Research |