| Bayamon Hotel Company LLC | Accommodation and Food Services | $1,460,500 | $1,478,594 | 128 | $40.0M |  Research |
| Tasis Dorado Educational Foundation INC | Educational Services | $1,400,200 | $1,412,880 | 157 | N/A | Research |
| Master Paints and Chemical Corporation | Manufacturing | $1,367,700 | $1,382,669 | 200 | $198.4M | Research |
| Caribe Holdings Cayman Co Ltd | Manufacturing | $1,200,900 | $1,208,372 | 138 | $136.9M | Research |
| Caribe Holdings Cayman Co Ltd | Manufacturing | $1,180,000 | $1,190,882 | 155 | $153.7M | Research |
| Pharma Serv INC | Professional, Scientific, and Technical Services | $1,080,400 | $1,094,385 | 82 | $8.5M | Research |
| Manati Hotel Company LLC | Accommodation and Food Services | $1,076,800 | $1,090,200 | 103 | $32.2M | Research |
| Bayamon Hotel Company LLC | Accommodation and Food Services | $1,043,200 | $1,056,269 | 173 | $54.1M | Research |
| Manati Hotel Company LLC | Accommodation and Food Services | $769,100 | $778,479 | 111 | $34.7M | Research |
| Pharma Bio Serve Pr INC | Professional, Scientific, and Technical Services | $757,100 | $766,900 | 58 | $6.0M | Research |
| Pepe Gangas, Corp. | Retail Trade | $755,239 | $801,117 | 240 | $56.5M | Research |
| District Hotel Partners LLC | Accommodation and Food Services | $477,700 | $482,888 | 22 | $6.9M | Research |
| Pvma Global LLC | Professional, Scientific, and Technical Services | $450,000 | $431,426 | 8 | <$5M | Research |
| Dl Hotel Company LLC | Accommodation and Food Services | $415,200 | $295,858 | 30 | $9.4M | Research |
| Supermercados Selectos INC | Retail Trade | $408,000 | $416,443 | 75 | $18.7M | Research |
| Optima Infusion Pharmacy, Inc. | Retail Trade | $401,500 | $405,392 | 81 | $14.1M | Research |
| District Hotel Company LLC | Accommodation and Food Services | $387,900 | $392,188 | 20 | $6.3M | Research |
| District Hotel Partners, LLC | Accommodation and Food Services | $341,000 | $297,214 | 75 | $23.5M | Research |
| Metropol Dorado INC | Accommodation and Food Services | $308,300 | $311,272 | 52 | $9.2M | Research |
| Dl Hotel Company LLC | Accommodation and Food Services | $297,600 | $300,118 | 33 | $10.3M | Research |
| El Caballin Dorado Corp. | Accommodation and Food Services | $287,140 | $291,056 | 37 | $6.6M | Research |
| District Hotel Company, LLC | Accommodation and Food Services | $277,000 | $280,362 | 54 | $16.9M | Research |
| Puerto Rico Alarm Systems INC | Administrative and Support and Waste Management | $266,100 | $268,524 | 24 | <$5M | Research |
| Dorado Condominium SE | Accommodation and Food Services | $240,600 | $242,932 | 40 | $12.5M | Research |
| Metropol Dorado, Inc. | Accommodation and Food Services | $220,700 | $223,054 | 85 | $15.1M | Research |