| Tropical Asphalt Solutions Corp | Construction | $54,700 | $55,072 | 24 | $7.4M | AI Deep Dive |
| Isabela Bakery Corp | Manufacturing | $52,300 | $52,567 | 28 | $9.9M | AI Deep Dive |
| Farmacia Las Colinas Isabela, INC | Unknown | $51,500 | $51,932 | 13 | N/A | AI Deep Dive |
| Asociacion Nacional De Ciegos Capitulo De Isabela INC | Health Care and Social Assistance | $51,400 | $51,774 | 12 | N/A | AI Deep Dive |
| Boca INC | Accommodation and Food Services | $50,700 | $50,948 | 22 | $6.9M | AI Deep Dive |
| Advance Roofing Depot INC | Wholesale Trade | $49,610 | $50,066 | 13 | <$5M | AI Deep Dive |
| Isabela Bakery Corp | Unknown | $47,500 | $47,896 | 31 | N/A | AI Deep Dive |
| Maba Corp. | Construction | $45,400 | $45,744 | 18 | $6.1M | AI Deep Dive |
| Jjj Enterprises LLC | Accommodation and Food Services | $44,800 | $45,106 | 20 | <$5M | AI Deep Dive |
| Sistema Integrado De Salud Del Oeste, LLC | Health Care and Social Assistance | $43,900 | $44,446 | 5 | <$5M | AI Deep Dive |
| Laboratorio Clinico Rq | Health Care and Social Assistance | $43,800 | $44,045 | 6 | <$5M | AI Deep Dive |
| Raquel Quinones Morales | Health Care and Social Assistance | $43,500 | $43,711 | 6 | <$5M | AI Deep Dive |
| Velazquez & Co Psc CPA | Professional, Scientific, and Technical Services | $41,200 | $41,498 | 6 | <$5M | AI Deep Dive |
| Velazquez & Co Psc CPA | Professional, Scientific, and Technical Services | $41,200 | $41,403 | 6 | <$5M | AI Deep Dive |
| Costa Isabela Partners Inc. | Administrative and Support and Waste Management | $41,100 | $41,482 | 5 | <$5M | AI Deep Dive |
| Costa Isabela Partners INC | Real Estate and Rental and Leasing | $41,100 | $41,300 | 4 | <$5M | AI Deep Dive |
| El Criollo Sandwich INC | Accommodation and Food Services | $40,800 | $41,371 | 14 | <$5M | AI Deep Dive |
| El Farmer, INC | Agriculture, Forestry, Fishing and Hunting | $40,730 | $41,002 | 12 | <$5M | AI Deep Dive |
| Rinconcito De Amor INC | Health Care and Social Assistance | $40,600 | $40,987 | 29 | <$5M | AI Deep Dive |
| Dga Selectos Restaurant LLC | Accommodation and Food Services | $40,000 | $40,460 | 26 | <$5M | AI Deep Dive |
| Farmacia Los Angeles De Isabela LLC | Retail Trade | $39,800 | $40,231 | 11 | <$5M | AI Deep Dive |
| Carlos Roman Dairy Farm Inc. | Agriculture, Forestry, Fishing and Hunting | $38,500 | $38,770 | 14 | <$5M | AI Deep Dive |
| Waldo Santiago Arocho | Accommodation and Food Services | $38,000 | $38,409 | 5 | <$5M | AI Deep Dive |
| Boca INC | Unknown | $37,500 | $37,772 | 18 | N/A | AI Deep Dive |
| Advanced Soil Engineering Psc | Professional, Scientific, and Technical Services | $37,400 | $37,620 | 11 | <$5M | AI Deep Dive |