| Kvh Industries INC | Manufacturing | $6,927,172 | $7,022,065 | 419 | $109.7M | Research |
| Looking Upwards | Other Services (except Public Administration) | $3,611,800 | $3,657,951 | 500 | N/A | Research |
| Purvis Systems Incorporated | Professional, Scientific, and Technical Services | $2,169,800 | $2,193,995 | 131 | $16.2M | Research |
| Network and Simulation Technologies INC | Information | $1,926,800 | $0 | 113 | $19.0M | Research |
| James L Maher Center | Other Services (except Public Administration) | $1,615,500 | $1,631,168 | 270 | N/A | Research |
| Child and Family Services of Newport County INC | Other Services (except Public Administration) | $1,329,278 | $1,337,734 | 134 | N/A | Research |
| Seaview Hotel INC | Accommodation and Food Services | $1,301,718 | $1,311,336 | 133 | $41.6M | Research |
| Child and Family Services of Newport County, Inc. | Health Care and Social Assistance | $1,293,500 | $1,304,603 | 143 | N/A | Research |
| Newport Vineyards & Winery LLC | Accommodation and Food Services | $1,225,756 | $1,232,439 | 60 | $10.7M | Research |
| Kirby Perkins Constructions INC | Construction | $1,184,504 | $1,198,815 | 82 | $24.9M | Research |
| Kirby Perkins Construction,inc. | Construction | $1,184,500 | $1,194,722 | 58 | $17.6M | Research |
| Newport County Community Mental Health Center | Health Care and Social Assistance | $955,500 | $962,830 | 108 | N/A | Research |
| Seaview Hotel INC | Accommodation and Food Services | $929,700 | $938,080 | 200 | $62.5M | Research |
| Towerstream I INC | Information | $808,905 | $815,709 | 48 | $8.1M | Research |
| Saccucci Auto Group, INC | Retail Trade | $781,700 | $791,616 | 59 | $14.9M | Research |
| Langway of Newport INC | Retail Trade | $771,300 | $694,726 | 48 | $12.1M | Research |
| Mdr Enterprises LLC | Retail Trade | $764,812 | $769,210 | 52 | $13.1M | Research |
| Aspire Dermatology | Health Care and Social Assistance | $742,600 | $753,302 | 60 | $18.8M | Research |
| Newport Vineyards & Winery, LLC | Manufacturing | $732,800 | $739,747 | 60 | $21.2M | Research |
| Pierce Agency of Portsmouth, INC | Finance and Insurance | $676,600 | $682,995 | 44 | $22.6M | Research |
| Mdr Enterprises LLC | Retail Trade | $598,400 | $772,427 | 52 | $13.1M | Research |
| The John Clarke Retirement Center | Retail Trade | $563,900 | $567,608 | 74 | N/A | Research |
| Marine Acoustics INC | Professional, Scientific, and Technical Services | $543,500 | $549,024 | 27 | <$5M | Research |
| Dk Catering LLC | Accommodation and Food Services | $540,547 | $543,460 | 119 | $22.2M | Research |
| Newport Hotel Group, LLC | Accommodation and Food Services | $515,000 | $521,294 | 38 | $11.9M | Research |