| Abbeville Area Medical Center | Health Care and Social Assistance | $4,934,400 | $4,988,881 | 387 | N/A |  Research |
| Burnstein Von Seelen Precision Castings Corporation | Manufacturing | $2,164,200 | $2,191,119 | 245 | $64.1M | Research |
| Stoll Industries Incorporated | Wholesale Trade | $836,000 | $843,833 | 74 | $22.7M | Research |
| Stoll Industries, Inc. | Manufacturing | $741,200 | $747,109 | 75 | $19.6M | Research |
| Reelco of Abbeville, Incorporated | Manufacturing | $710,160 | $719,491 | 78 | $77.4M | Research |
| Little River Electric Cooperative, Inc. | Public Administration | $675,820 | $680,708 | 31 | N/A | Research |
| Merl's Countertops,inc | Construction | $329,833 | $331,731 | 36 | $10.9M | Research |
| The Village Grill INC | Accommodation and Food Services | $222,806 | $223,832 | 34 | $6.0M | Research |
| Stoll Trailers, INC | Manufacturing | $202,034 | $203,180 | 17 | <$5M | Research |
| Smith's Termite and Pest Control INC | Administrative and Support and Waste Management | $170,600 | $172,124 | 12 | <$5M | Research |
| The Village Grill | Accommodation and Food Services | $159,202 | $160,445 | 50 | $8.9M | Research |
| Camille Mason MD PA | Health Care and Social Assistance | $153,084 | $154,032 | 16 | $5.0M | Research |
| Camile Mason MD PA | Health Care and Social Assistance | $153,000 | $153,948 | 16 | $5.0M | Research |
| Ksc Logistics, Inc. | Professional, Scientific, and Technical Services | $148,853 | $150,076 | 20 | <$5M | Research |
| Environmental Landscaping Inc. | Construction | $137,300 | $138,154 | 19 | $6.5M | Research |
| Communication Connectors LLC | Construction | $136,700 | $137,453 | 15 | <$5M | Research |
| Wades of Abbeville, Inc. | Retail Trade | $130,300 | $131,208 | 15 | <$5M | Research |
| Carolina Arena Equipment LLC | Manufacturing | $106,190 | $106,653 | 10 | <$5M | Research |
| Hite and Stone Attorneys at Law LLC | Professional, Scientific, and Technical Services | $103,193 | $103,578 | 9 | <$5M | Research |
| Fishers Storage Barns Incorporated | Manufacturing | $99,300 | $99,980 | 12 | $11.9M | Research |
| Spires Logging Inc. | Agriculture, Forestry, Fishing and Hunting | $90,500 | $90,855 | 10 | <$5M | Research |
| Spires Logging, Inc. | Retail Trade | $90,500 | $90,951 | 12 | <$5M | Research |
| Hite and Stone, LLC | Professional, Scientific, and Technical Services | $90,174 | $90,569 | 7 | <$5M | Research |
| Lawson Family Dental Care LLC | Health Care and Social Assistance | $83,591 | $84,052 | 9 | <$5M | Research |
| Lawson Family Dental Care LLC | Health Care and Social Assistance | $82,743 | $83,038 | 9 | <$5M | Research |