| Fowler Corporation | Construction | $451,400 | $455,147 | 36 | $11.2M | AI Deep Dive |
| Tactical Medical Solutions LLC | Manufacturing | $448,833 | $451,302 | 45 | $12.6M | AI Deep Dive |
| Young Men's Christian Association of Anderson, Inc. | Other Services (except Public Administration) | $447,200 | $451,995 | 397 | N/A | AI Deep Dive |
| The Walker Agency, Inc. of Anderson | Finance and Insurance | $432,301 | $436,174 | 44 | $22.6M | AI Deep Dive |
| Consolidated Southern Industries, Inc. | Manufacturing | $419,760 | $422,395 | 48 | $11.7M | AI Deep Dive |
| Dietze & Schell Manufacturing | Manufacturing | $411,777 | $353,617 | 25 | $6.5M | AI Deep Dive |
| Ymca of Anderson Sc | Other Services (except Public Administration) | $408,375 | $411,495 | 245 | N/A | AI Deep Dive |
| Harris Carpet and Linoleum INC | Retail Trade | $406,400 | $410,362 | 34 | $6.2M | AI Deep Dive |
| Medicus Eye Group PA | Health Care and Social Assistance | $406,200 | $408,897 | 36 | $8.4M | AI Deep Dive |
| Medicus Eye Group PA | Health Care and Social Assistance | $406,200 | $409,766 | 39 | $9.1M | AI Deep Dive |
| Electric City Masonry, LLC | Construction | $405,800 | $408,224 | 36 | <$5M | AI Deep Dive |
| Staffworks LLC | Administrative and Support and Waste Management | $399,700 | $402,576 | 81 | $12.7M | AI Deep Dive |
| Suburban Contractors LLC | Professional, Scientific, and Technical Services | $399,267 | $404,490 | 35 | <$5M | AI Deep Dive |
| Skins Inc. | Accommodation and Food Services | $376,100 | $378,769 | 118 | $21.0M | AI Deep Dive |
| General Machine of Anderson, Inc. | Manufacturing | $375,000 | $366,871 | 36 | $8.8M | AI Deep Dive |
| Hytech Machining Inc. | Manufacturing | $372,700 | $376,510 | 27 | $6.6M | AI Deep Dive |
| Sullivans Metropolitan Grill INC | Accommodation and Food Services | $365,536 | $368,196 | 52 | $9.2M | AI Deep Dive |
| Caring Hands Home Care of the Upstate, Inc. | Health Care and Social Assistance | $362,845 | $366,135 | 130 | $22.3M | AI Deep Dive |
| Anesthesiology Services of Anderson PA | Health Care and Social Assistance | $357,000 | $361,008 | 9 | <$5M | AI Deep Dive |
| Gilmer & Sons Mobile Home Sales | Retail Trade | $354,504 | $59,985 | 9 | <$5M | AI Deep Dive |
| Anderson Skin and Cancer Clinic | Health Care and Social Assistance | $350,400 | $352,272 | 37 | $11.6M | AI Deep Dive |
| Jpm Trucking Inc. | Transportation and Warehousing | $350,000 | $353,801 | 34 | $5.1M | AI Deep Dive |
| Selem Corporation INC | Accommodation and Food Services | $350,000 | $351,915 | 65 | $11.5M | AI Deep Dive |
| Glenn Mechanical Co., LLC | Construction | $343,125 | $347,882 | 40 | $13.6M | AI Deep Dive |
| Glenn Mechanical Co. LLC | Construction | $343,125 | $7,490 | 33 | $11.2M | AI Deep Dive |