| Robert Collins | Construction | $458,526 | $458,588 | 51 | $19.1M | AI Deep Dive |
| Anderson Oil Company Inc. | Retail Trade | $450,958 | $453,062 | 124 | $41.5M | AI Deep Dive |
| Anderson Oil Company INC | Retail Trade | $450,149 | $452,884 | 126 | $42.2M | AI Deep Dive |
| Wade's Repair Service, Inc. | Construction | $315,000 | $316,614 | 25 | $7.9M | AI Deep Dive |
| B&b Ford, INC | Other Services (except Public Administration) | $192,000 | $193,583 | 23 | <$5M | AI Deep Dive |
| Southern Carolina Regional | Professional, Scientific, and Technical Services | $175,500 | $177,318 | 1 | <$5M | AI Deep Dive |
| First Baptist Church of Barnwell | Other Services (except Public Administration) | $174,700 | $175,811 | 34 | N/A | AI Deep Dive |
| Still & Reece Dentistry LLC | Health Care and Social Assistance | $168,400 | $169,558 | 15 | <$5M | AI Deep Dive |
| Still & Reece Dentistry, LLC | Health Care and Social Assistance | $156,700 | $157,876 | 15 | <$5M | AI Deep Dive |
| First Baptist Church of Barnwell | Other Services (except Public Administration) | $123,600 | $124,352 | 32 | N/A | AI Deep Dive |
| Safe Logging LLC | Agriculture, Forestry, Fishing and Hunting | $123,027 | $132,352 | 14 | <$5M | AI Deep Dive |
| Chappell Farms INC | Agriculture, Forestry, Fishing and Hunting | $102,600 | $103,519 | 20 | <$5M | AI Deep Dive |
| J. Michael Barley | Accommodation and Food Services | $99,100 | $100,254 | 35 | <$5M | AI Deep Dive |
| Palmetto Tool Inc. | Professional, Scientific, and Technical Services | $97,500 | $98,090 | 16 | <$5M | AI Deep Dive |
| Gordon Padgett | Professional, Scientific, and Technical Services | $94,129 | $94,619 | 18 | <$5M | AI Deep Dive |
| Barnwell Health Investors | Retail Trade | $91,200 | $91,922 | 14 | <$5M | AI Deep Dive |
| Moore Industrial Services LLC | Administrative and Support and Waste Management | $90,300 | $90,777 | 14 | <$5M | AI Deep Dive |
| Palmetto Truck and Trailer Service LLC | Transportation and Warehousing | $89,100 | $89,747 | 8 | <$5M | AI Deep Dive |
| Barnwell County Commission On Alcohol and Drug Abuse | Health Care and Social Assistance | $89,000 | $58,217 | 11 | <$5M | AI Deep Dive |
| Twitty's Tree Service, Inc. | Professional, Scientific, and Technical Services | $88,400 | $89,214 | 10 | <$5M | AI Deep Dive |
| Sra Track LLC | Manufacturing | $88,300 | $88,859 | 48 | $12.6M | AI Deep Dive |
| Palmetto Tools Inc. | Manufacturing | $85,100 | $85,676 | 12 | <$5M | AI Deep Dive |
| Generations Unlimited | Health Care and Social Assistance | $85,000 | $85,941 | 35 | N/A | AI Deep Dive |
| Gordon T Padgett | Professional, Scientific, and Technical Services | $75,336 | $75,654 | 18 | <$5M | AI Deep Dive |
| Tri County Pallet Co INC | Manufacturing | $75,300 | $75,975 | 16 | $15.9M | AI Deep Dive |