| W. O. Cantey Services, INC | Construction | $1,535,000 | $1,550,648 | 113 | $26.1M |  Research |
| Kershawhealth | Health Care and Social Assistance | $1,381,300 | $1,408,888 | 121 | N/A | Research |
| Outlaw Enterprises, Inc. | Accommodation and Food Services | $1,256,100 | $1,271,311 | 325 | $57.7M | Research |
| Camden Military Academy | Educational Services | $777,000 | $783,518 | 109 | N/A | Research |
| Carolina's Contracting LLC | Construction | $608,677 | $614,662 | 50 | $15.5M | Research |
| Smith Robinson Holler Dubose and Morgan, LLC | Professional, Scientific, and Technical Services | $470,700 | $473,562 | 39 | $9.5M | Research |
| Sheheen Hancock & Godwin, LLP | Professional, Scientific, and Technical Services | $465,000 | $468,554 | 33 | $10.5M | Research |
| Allstaff Employment Services | Administrative and Support and Waste Management | $407,278 | $410,022 | 71 | $11.2M | Research |
| Speaks Oil Company, INC | Retail Trade | $384,200 | $387,700 | 42 | $14.1M | Research |
| Coastal Operations LLC | Accommodation and Food Services | $333,400 | $336,981 | 10 | <$5M | Research |
| Kershaw County Commission On Alcohol and Drug Abuse | Health Care and Social Assistance | $331,970 | $335,207 | 34 | N/A | Research |
| Industrial Waste Recovery, LLC | Administrative and Support and Waste Management | $324,288 | $326,455 | 20 | <$5M | Research |
| Pediatric Associates of Kershaw County | Health Care and Social Assistance | $306,000 | $308,729 | 29 | $9.1M | Research |
| Pediatric Associates of Kershaw County | Health Care and Social Assistance | $299,648 | $302,794 | 19 | $6.0M | Research |
| Galloway Enterprises INC | Accommodation and Food Services | $284,740 | $286,573 | 54 | $9.6M | Research |
| Kershaw County Commission On Alcohol and Drug Abuse | Other Services (except Public Administration) | $283,822 | $285,809 | 29 | N/A | Research |
| First Baptist Church Camden | Other Services (except Public Administration) | $270,500 | $274,347 | 29 | N/A | Research |
| Frazier Service Company LLC | Accommodation and Food Services | $261,900 | $264,684 | 10 | <$5M | Research |
| Savage, Royall, & Sheheen, LLP | Professional, Scientific, and Technical Services | $245,994 | $248,690 | 19 | <$5M | Research |
| Wateree Animal Hospitals, Inc. | Other Services (except Public Administration) | $244,553 | $246,342 | 35 | $6.7M | Research |
| Camden Bone and Joint LLC | Health Care and Social Assistance | $217,983 | $219,608 | 22 | $6.9M | Research |
| Upchurch & Jowers Insurance Agency, INC | Finance and Insurance | $217,700 | $219,641 | 14 | $7.2M | Research |
| Sam Kendall LLC | Accommodation and Food Services | $198,625 | $200,109 | 38 | $6.7M | Research |
| Semper Fi Industrial Coatings INC | Unknown | $197,000 | $148,636 | 18 | N/A | Research |
| Retireease Senior Services INC | Health Care and Social Assistance | $195,500 | $196,608 | 60 | $10.3M | Research |