| Colliers International of Sc | Real Estate and Rental and Leasing | $1,493,740 | $1,499,798 | 109 | $16.4M | Research |
| Mccrory Construction Company, LLC | Construction | $1,491,827 | $1,502,617 | 87 | $99.1M | Research |
| Colliers International South Carolina, I | Real Estate and Rental and Leasing | $1,487,597 | $1,503,837 | 106 | $15.9M | Research |
| Softdocs Inc. | Information | $1,428,500 | $0 | 102 | $17.1M | Research |
| Galeana Chrysler Jeep Inc. | Retail Trade | $1,421,940 | $1,434,263 | 119 | $30.0M | Research |
| Sc Baptist Convention | Other Services (except Public Administration) | $1,404,047 | $1,418,241 | 254 | N/A | Research |
| Access Healthcare Services, LLC | Health Care and Social Assistance | $1,383,900 | $1,401,796 | 310 | $53.1M | Research |
| Carolina Anesthesiology Associates, P.a. | Health Care and Social Assistance | $1,366,354 | $1,384,041 | 42 | $13.2M | Research |
| Epworth Children's Home | Health Care and Social Assistance | $1,343,300 | $1,354,341 | 138 | N/A | Research |
| Dp Professionals, Inc. | Administrative and Support and Waste Management | $1,316,522 | $1,325,811 | 84 | $13.2M | Research |
| Allen University | Educational Services | $1,310,155 | $1,322,000 | 150 | N/A | Research |
| Tlc Enterprises, LLC | Accommodation and Food Services | $1,310,000 | $1,327,515 | 420 | $74.6M | Research |
| Pitts Radiological Associates, P.a. | Health Care and Social Assistance | $1,275,370 | $1,292,268 | 41 | $12.9M | Research |
| Richardson Plowden & Robinson P.a. | Other Services (except Public Administration) | $1,275,000 | $0 | 78 | $14.9M | Research |
| Central Electric Power Company, Inc. | Utilities | $1,243,670 | $1,259,492 | 49 | N/A | Research |
| Hood Construction Company INC | Construction | $1,241,500 | $1,252,639 | 77 | $87.7M | Research |
| Rogers Townsend LLC | Professional, Scientific, and Technical Services | $1,237,500 | $1,249,291 | 89 | $21.6M | Research |
| Kenneth Shuler's School of Cosmetology Inc. | Educational Services | $1,212,300 | $1,222,563 | 159 | $33.4M | Research |
| The Cason Group INC | Finance and Insurance | $1,208,700 | $1,219,379 | 116 | $59.6M | Research |
| Corner Pantry, Inc. | Retail Trade | $1,205,926 | $1,212,468 | 177 | $59.2M | Research |
| Corner Pantry Inc. | Retail Trade | $1,205,900 | $1,212,772 | 177 | $59.2M | Research |
| W,o. Blackstone & Co. INC | Construction | $1,183,864 | $1,193,497 | 111 | $35.1M | Research |
| Kenneth Shuler's School of Cosmetology Inc. | Educational Services | $1,177,300 | $1,189,525 | 1 | <$5M | Research |
| Rei Automation, Inc. | Construction | $1,172,195 | $0 | 67 | $22.8M | Research |
| Shealy's INC | Wholesale Trade | $1,167,500 | $1,179,175 | 100 | $30.6M | Research |