| Southern Asphalt, INC | Manufacturing | $2,047,800 | $2,072,149 | 230 | $228.1M |  Research |
| Southern Asphalt INC | Construction | $2,000,000 | $2,008,877 | 230 | $71.3M | Research |
| Canal Wood, LLC | Agriculture, Forestry, Fishing and Hunting | $1,862,100 | $1,875,364 | 108 | $11.0M | Research |
| Southeast Woodland Services INC | Agriculture, Forestry, Fishing and Hunting | $1,720,936 | $1,732,252 | 214 | $10.8M | Research |
| Horry County Disabilities & Special Needs | Health Care and Social Assistance | $1,341,477 | $1,359,326 | 153 | $24.8M | Research |
| Conway Manor LLC | Health Care and Social Assistance | $1,275,406 | $1,289,838 | 173 | $29.4M | Research |
| Hadwin White Buick Gmc INC | Retail Trade | $1,085,100 | $1,092,274 | 85 | $21.4M | Research |
| Southeast Woodland Services, INC | Agriculture, Forestry, Fishing and Hunting | $948,317 | $958,735 | 44 | <$5M | Research |
| Conway Ford INC | Retail Trade | $925,065 | $932,237 | 83 | $20.9M | Research |
| Heritage Hauling INC | Transportation and Warehousing | $875,500 | $883,320 | 89 | $13.5M | Research |
| Heritage Hauling Inc. | Transportation and Warehousing | $832,500 | $839,502 | 89 | $23.8M | Research |
| Chippewa Aerospace, Inc. | Manufacturing | $819,170 | $828,708 | 68 | $17.8M | Research |
| King Construction Service INC | Construction | $804,000 | $809,397 | 105 | $31.9M | Research |
| D & L Sitework INC | Construction | $777,286 | $780,246 | 84 | $31.5M | Research |
| Horry County Commission On Alcohol and Drug Abuse | Health Care and Social Assistance | $755,037 | $757,705 | 64 | N/A | Research |
| Coastal Asphalt, LLC | Manufacturing | $754,500 | $758,734 | 82 | $81.3M | Research |
| Horry County Commission On Alcohol and Drug Abuse | Health Care and Social Assistance | $741,300 | $745,382 | 65 | N/A | Research |
| Billy's Plumbing Company LLC | Construction | $735,300 | $740,215 | 93 | $29.4M | Research |
| Palmetto Chevrolet Co, INC | Retail Trade | $672,600 | $676,875 | 58 | $14.6M | Research |
| Omni Services of South Carolina, INC | Construction | $667,258 | $672,892 | 63 | $20.7M | Research |
| D & L Sitework INC | Construction | $646,300 | $649,912 | 54 | $20.2M | Research |
| Carolina Pavement Markings INC | Professional, Scientific, and Technical Services | $644,375 | $647,553 | 83 | $11.6M | Research |
| Chippewa Aerospace INC | Manufacturing | $641,584 | $646,682 | 77 | $20.2M | Research |
| Teknoware, INC | Manufacturing | $611,300 | $616,492 | 60 | $15.7M | Research |
| Spann Roofing and Sheet Metal, Inc. | Construction | $604,000 | $610,255 | 50 | $16.5M | Research |