| John Harris Body Shops | Other Services (except Public Administration) | $3,160,220 | $3,196,411 | 273 | $53.5M |  Research |
| Great Southern Homes, INC | Construction | $1,693,800 | $1,703,563 | 174 | $52.9M | Research |
| Clark's Termite & Pest Control Fka Arrow Exterminating Compa | Administrative and Support and Waste Management | $1,508,200 | $1,517,043 | 187 | $40.5M | Research |
| Labor Finders of South Carolina | Administrative and Support and Waste Management | $1,359,593 | $1,371,364 | 396 | $62.3M | Research |
| Labor Finders of South Carolina | Administrative and Support and Waste Management | $1,352,212 | $1,364,178 | 225 | $35.4M | Research |
| Advanced Video Group, Inc. | Construction | $1,308,082 | $384,189 | 27 | $8.9M | Research |
| Diesel Laptops LLC | Professional, Scientific, and Technical Services | $1,289,540 | $1,296,677 | 140 | $29.0M | Research |
| Jim Hudson Superstore, Inc. | Retail Trade | $1,109,800 | $1,116,089 | 143 | $36.0M | Research |
| St. Andrews Fitness Corporation | Real Estate and Rental and Leasing | $1,072,000 | $1,085,698 | 147 | $22.1M | Research |
| Contract Construction, Inc. | Construction | $1,045,500 | $1,053,979 | 55 | $12.7M | Research |
| Coogler Construction, INC | Construction | $1,044,693 | $1,060,607 | 115 | $43.1M | Research |
| Southland Log Homes LLC | Manufacturing | $971,885 | $981,550 | 47 | $46.6M | Research |
| Southland Log Homes LLC | Manufacturing | $971,885 | $985,329 | 40 | $39.7M | Research |
| Coogler Construction INC | Construction | $953,130 | $961,121 | 105 | $39.3M | Research |
| Cassell Brothers Heating and Cooling, LLC | Construction | $793,440 | $802,388 | 67 | $21.2M | Research |
| St. Andrews Fitness Corporation | Arts, Entertainment, and Recreation | $765,146 | $775,263 | 180 | $25.2M | Research |
| South Carolina Internal Medicine Associates and Rehabilitati | Health Care and Social Assistance | $663,774 | $667,957 | 67 | $21.0M | Research |
| Pyramid Contracting LLC | Construction | $650,200 | $655,907 | 63 | $71.8M | Research |
| Advanced Automation Consulting INC | Professional, Scientific, and Technical Services | $579,300 | $582,458 | 33 | <$5M | Research |
| Riverland Hills Baptist Church | Other Services (except Public Administration) | $562,500 | $566,990 | 94 | N/A | Research |
| Sansbury Eye Center, Inc. | Health Care and Social Assistance | $552,500 | $558,767 | 58 | $13.6M | Research |
| Pella Window & Door | Manufacturing | $492,100 | $495,025 | 33 | $32.7M | Research |
| Advanced Video Group Inc. | Construction | $488,100 | $489,852 | 27 | $8.9M | Research |
| Integrated Micro-Chromatography Systems Inc. | Manufacturing | $451,400 | $456,087 | 36 | $35.7M | Research |
| Integrated Micro-Chromatography Systems Inc. | Professional, Scientific, and Technical Services | $451,400 | $456,866 | 36 | $7.4M | Research |