| Log Creek Thinning INC | Agriculture, Forestry, Fishing and Hunting | $581,000 | $588,450 | 45 | <$5M |  Research |
| Carolina Farms & Harvesting INC | Agriculture, Forestry, Fishing and Hunting | $459,377 | $464,751 | 128 | $13.1M | Research |
| Log Creek Logging INC | Agriculture, Forestry, Fishing and Hunting | $450,000 | $455,659 | 42 | <$5M | Research |
| J. W. Yonce & Sons Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $234,800 | $237,740 | 39 | <$5M | Research |
| Francis Hugh Wardlaw Academy | Educational Services | $168,000 | $169,717 | 26 | <$5M | Research |
| Homecare South Services, LLC | Health Care and Social Assistance | $159,553 | $161,345 | 90 | $14.6M | Research |
| Joseph Michael Saye | Unknown | $101,700 | $102,207 | 13 | N/A | Research |
| Three Star Vineyard and Orchard of Johnston LLC | Agriculture, Forestry, Fishing and Hunting | $72,526 | $72,901 | 12 | <$5M | Research |
| Johnston Animal Hospital LLC | Professional, Scientific, and Technical Services | $68,100 | $68,738 | 11 | <$5M | Research |
| Tidwell Jewelers LLC | Retail Trade | $67,100 | $67,782 | 12 | <$5M | Research |
| Forrest's Tire Service, Inc. | Retail Trade | $64,000 | $64,788 | 8 | <$5M | Research |
| Quad Enterprises LLC | Retail Trade | $60,800 | $61,475 | 6 | <$5M | Research |
| Three Star Vineyard and Orchard of Johnston LLC | Agriculture, Forestry, Fishing and Hunting | $56,515 | $57,074 | 5 | <$5M | Research |
| Thomas Long | Finance and Insurance | $47,400 | $47,817 | 4 | <$5M | Research |
| Maxwell & Halford Drug INC | Retail Trade | $46,500 | $46,910 | 5 | <$5M | Research |
| Spanky's Service Center LLC | Other Services (except Public Administration) | $40,000 | $40,423 | 5 | <$5M | Research |
| Quin Jarvis Enterprise LLC | Accommodation and Food Services | $39,574 | $0 | 10 | <$5M | Research |
| W Hugh Morgan MD | Health Care and Social Assistance | $35,000 | $35,365 | 5 | <$5M | Research |
| Willis Pool Construction LLC | Construction | $30,400 | $30,548 | 2 | <$5M | Research |
| Doley Lamb | Construction | $30,200 | $30,336 | 3 | <$5M | Research |
| Quin Jarvis Enterprise LLC | Accommodation and Food Services | $28,280 | $0 | 10 | <$5M | Research |
| Emaa Enterprise LLC | Professional, Scientific, and Technical Services | $28,260 | $28,482 | 7 | <$5M | Research |
| Emaa Enterprise LLC | Finance and Insurance | $23,600 | $28,002 | 5 | <$5M | Research |
| Edgefield-Saluda Radio Company Inc. | Information | $21,100 | $21,286 | 5 | <$5M | Research |
| Jane Herlong | Arts, Entertainment, and Recreation | $20,833 | $20,995 | 1 | <$5M | Research |