| Miles Holding Compnay LLC | Construction | $1,034,700 | $1,040,650 | 74 | $23.4M | Research |
| Anastopoulo Law Firm, LLC | Professional, Scientific, and Technical Services | $1,030,520 | $1,037,991 | 95 | $23.1M | Research |
| Asset Management & Consulting Services, Inc. | Real Estate and Rental and Leasing | $1,016,693 | $1,023,127 | 95 | $14.3M | Research |
| Charleston Shoe Company, LLC | Retail Trade | $1,008,600 | $976,507 | 135 | $37.3M | Research |
| Limehouse Produce Inc. | Wholesale Trade | $972,100 | $981,555 | 66 | $17.0M | Research |
| Joye Law Firm LLP | Professional, Scientific, and Technical Services | $964,108 | $974,713 | 55 | $13.4M | Research |
| Td North Charleston Hotel LLC | Accommodation and Food Services | $945,700 | $953,473 | 50 | $15.6M | Research |
| Mission Solutions Group INC | Real Estate and Rental and Leasing | $891,200 | $899,666 | 51 | $7.7M | Research |
| Joye Law Firm, LLP | Professional, Scientific, and Technical Services | $887,600 | $899,410 | 49 | $11.9M | Research |
| Charles Blanchard Construction | Construction | $883,600 | $891,479 | 71 | $21.6M | Research |
| C R Hipp Construction, Inc. | Other Services (except Public Administration) | $879,495 | $885,085 | 80 | $15.7M | Research |
| Husk Nash Inc. | Accommodation and Food Services | $875,171 | $878,864 | 34 | $6.0M | Research |
| Superior Transportation Inc. | Transportation and Warehousing | $867,620 | $874,395 | 58 | $8.8M | Research |
| Michael Business Machines Corporation | Wholesale Trade | $850,886 | $856,487 | 36 | $11.0M | Research |
| Dig in the Park LLC | Accommodation and Food Services | $848,194 | $860,186 | 92 | $16.3M | Research |
| Preferred Home Services, LLC | Construction | $847,735 | $855,035 | 77 | $24.4M | Research |
| Michael Business Machines Corporation | Wholesale Trade | $843,535 | $847,823 | 36 | $11.0M | Research |
| Command Decisions Systems & Solutions, Inc. | Public Administration | $806,000 | $558,655 | 29 | N/A | Research |
| Command Decisions Systems & Solutions Inc. | Professional, Scientific, and Technical Services | $806,000 | $327,670 | 23 | <$5M | Research |
| Pain Specialists of Charleston, PA | Health Care and Social Assistance | $794,500 | $801,783 | 75 | $23.5M | Research |
| Neal Brothers Charleston INC | Transportation and Warehousing | $794,137 | $800,294 | 71 | $5.5M | Research |
| Liberty Fire Protection Inc. | Construction | $788,138 | $794,572 | 72 | $24.5M | Research |
| Liberty Fire Protection, Inc. | Construction | $788,137 | $796,450 | 72 | $24.5M | Research |
| Carolina Correctional Healthcare Management LLC | Professional, Scientific, and Technical Services | $748,318 | $758,651 | 38 | $5.3M | Research |
| Snyder Party Rental Inc. | Real Estate and Rental and Leasing | $743,700 | $752,991 | 117 | $52.9M | Research |