| Rd Enterprises of Myrtle Beach LLC | Accommodation and Food Services | $375,200 | $377,564 | 70 | $12.4M |  Research |
| Mcgonigal's Flamingo Motel Inc. | Accommodation and Food Services | $359,700 | $361,718 | 43 | $13.4M | Research |
| Mb Billy's LLC | Accommodation and Food Services | $358,000 | $360,436 | 73 | $13.0M | Research |
| Crazy Horse Saloon Restaurant Inc. | Accommodation and Food Services | $347,868 | $349,660 | 65 | $11.5M | Research |
| Dick's Last Resort of Myrtle Beach LLC | Accommodation and Food Services | $339,862 | $345,120 | 34 | $6.0M | Research |
| Shak Inc. | Accommodation and Food Services | $332,731 | $336,286 | 50 | $8.9M | Research |
| First Baptist Chruch North Myrtle Beach | Other Services (except Public Administration) | $328,623 | $165,376 | 30 | N/A | Research |
| White Point INC | Accommodation and Food Services | $321,244 | $322,565 | 61 | $10.8M | Research |
| Tilghman Beach Rental Group LLC | Accommodation and Food Services | $314,800 | $316,559 | 45 | $14.1M | Research |
| Ampd Myrtle LLC | Accommodation and Food Services | $312,100 | $316,764 | 69 | $12.3M | Research |
| Grand Strand Dining Group LLC | Accommodation and Food Services | $311,916 | $315,928 | 21 | <$5M | Research |
| T & B Concepts of Myrtle Beach LLC | Accommodation and Food Services | $304,000 | $305,941 | 36 | $6.4M | Research |
| On Point Animal Hospital, Inc. | Professional, Scientific, and Technical Services | $300,000 | $304,700 | 30 | <$5M | Research |
| Joe's Bar and Grill Inc. | Accommodation and Food Services | $281,500 | $282,814 | 30 | $5.3M | Research |
| The Surf Golf and Beach Club, Inc. | Arts, Entertainment, and Recreation | $280,600 | $282,564 | 49 | N/A | Research |
| Strand Gastrointestinal Endoscopy | Health Care and Social Assistance | $271,711 | $272,843 | 48 | $15.1M | Research |
| Macaroni INC | Accommodation and Food Services | $262,902 | $265,229 | 54 | $9.6M | Research |
| Sfg Furnishings & Accents, Inc. | Retail Trade | $260,573 | $263,293 | 10 | <$5M | Research |
| Mcgonigals Flamingo Motel INC | Accommodation and Food Services | $259,600 | $261,670 | 43 | $13.4M | Research |
| Anaid Khachatryan | Retail Trade | $253,511 | $0 | 1 | <$5M | Research |
| Golf Tourism Solutions | Professional, Scientific, and Technical Services | $250,600 | $252,811 | 13 | <$5M | Research |
| Crazy Horse Saloon Restaurant, Inc. | Accommodation and Food Services | $248,400 | $250,319 | 68 | $12.1M | Research |
| Pgkr Enterprises LLC | Accommodation and Food Services | $245,400 | $246,716 | 10 | <$5M | Research |
| Sandy Wings Llc. | Accommodation and Food Services | $243,100 | $244,410 | 24 | <$5M | Research |
| Shak, Inc. | Accommodation and Food Services | $237,665 | $240,270 | 100 | $17.8M | Research |