| Beaufort Jasper Hampton Comprehensive Health Services, Inc. | Health Care and Social Assistance | $2,818,400 | $2,850,420 | 305 | N/A | AI Deep Dive |
| Berkeley Hall Club INC | Real Estate and Rental and Leasing | $1,146,883 | $1,153,136 | 134 | $20.1M | AI Deep Dive |
| Mike Reichenbach Chevrolet, Inc. | Retail Trade | $581,400 | $588,167 | 44 | $11.1M | AI Deep Dive |
| C3 Golf, LLC | Arts, Entertainment, and Recreation | $578,000 | $534,177 | 55 | $7.7M | AI Deep Dive |
| Palmetto Pediatrics of the Lowcountry LLC | Health Care and Social Assistance | $351,520 | $353,128 | 28 | $8.8M | AI Deep Dive |
| Spring Island Property Owners Association | Real Estate and Rental and Leasing | $286,500 | $0 | 17 | N/A | AI Deep Dive |
| Okatie Construction LLC | Construction | $236,942 | $238,344 | 21 | $7.9M | AI Deep Dive |
| Okatie Construction, LLC | Construction | $236,942 | $239,390 | 17 | $6.4M | AI Deep Dive |
| Southeastern Management Services LLC | Administrative and Support and Waste Management | $199,900 | $202,476 | 29 | $5.5M | AI Deep Dive |
| Dermatology Associates of the Lowcountry, PC | Health Care and Social Assistance | $191,122 | $193,347 | 17 | $5.3M | AI Deep Dive |
| Taylor Consultants LLC | Professional, Scientific, and Technical Services | $190,782 | $192,570 | 35 | <$5M | AI Deep Dive |
| J & W Corporation of Greenwood | Administrative and Support and Waste Management | $172,457 | $175,002 | 52 | $16.4M | AI Deep Dive |
| Phoenix Financial Services, LLC | Professional, Scientific, and Technical Services | $153,200 | $154,954 | 9 | <$5M | AI Deep Dive |
| Elite Physical Therapy & Sports Performance LLC | Health Care and Social Assistance | $135,938 | $136,814 | 8 | <$5M | AI Deep Dive |
| Solomon Coyle LLC | Educational Services | $133,200 | $134,169 | 7 | <$5M | AI Deep Dive |
| Solomon Coyle LLC | Professional, Scientific, and Technical Services | $126,025 | $127,355 | 7 | <$5M | AI Deep Dive |
| Callawassie Island Property Owners Association | Real Estate and Rental and Leasing | $121,800 | $0 | 12 | N/A | AI Deep Dive |
| Elite Physical Therapy & Sports Performance | Health Care and Social Assistance | $119,863 | $121,568 | 7 | <$5M | AI Deep Dive |
| Davis and Wine Dental Associates LLC | Health Care and Social Assistance | $111,700 | $112,526 | 15 | <$5M | AI Deep Dive |
| Coastal Anesthesiology Associates LLC | Health Care and Social Assistance | $89,877 | $90,642 | 12 | <$5M | AI Deep Dive |
| Lowcountry Custom Built Homes INC | Construction | $87,615 | $88,204 | 6 | <$5M | AI Deep Dive |
| Smith Law LLC | Professional, Scientific, and Technical Services | $79,600 | $80,358 | 6 | <$5M | AI Deep Dive |
| G & T Restaurants LLC | Accommodation and Food Services | $76,069 | $76,521 | 8 | <$5M | AI Deep Dive |
| Kenneth Scott Builders, Inc. | Construction | $74,900 | $75,460 | 7 | <$5M | AI Deep Dive |
| Kenneth Scott Builders, Inc. | Construction | $74,900 | $75,179 | 8 | <$5M | AI Deep Dive |