| Central Plains Industries, LLC | Manufacturing | $356,300 | $358,711 | 34 | $8.3M |  Research |
| Dakota Style Foods, Inc. | Manufacturing | $274,300 | $276,045 | 30 | $10.6M | Research |
| Clark City Sd Skilled Nursing Facility LLC | Health Care and Social Assistance | $256,513 | $257,904 | 40 | $6.8M | Research |
| Westside Implement, INC | Wholesale Trade | $200,800 | $202,150 | 13 | <$5M | Research |
| Clark Family Dental Center LLC | Health Care and Social Assistance | $192,100 | $194,138 | 18 | <$5M | Research |
| Clark Family Dental Center LLC | Health Care and Social Assistance | $192,000 | $193,147 | 18 | <$5M | Research |
| Clark Community Oil Company | Retail Trade | $187,700 | $188,821 | 46 | $11.0M | Research |
| Westside Implement Inc. | Other Services (except Public Administration) | $174,402 | $175,400 | 15 | <$5M | Research |
| Fay Wookey Memorial INC | Health Care and Social Assistance | $104,500 | $105,049 | 21 | <$5M | Research |
| Dakota Butcher - Clark Inc. | Wholesale Trade | $82,700 | $83,264 | 18 | <$5M | Research |
| Coteau Cattle Co | Agriculture, Forestry, Fishing and Hunting | $69,700 | $70,277 | 7 | <$5M | Research |
| Coteau Cattle Co | Agriculture, Forestry, Fishing and Hunting | $69,700 | $70,004 | 7 | <$5M | Research |
| Terry Mudgett | Agriculture, Forestry, Fishing and Hunting | $69,500 | $69,987 | 1 | <$5M | Research |
| Boss Construction Inc. | Construction | $62,495 | $63,077 | 9 | <$5M | Research |
| Ctwildlife Management | Agriculture, Forestry, Fishing and Hunting | $59,930 | $60,426 | 6 | <$5M | Research |
| Duenwald Transportation | Transportation and Warehousing | $56,250 | $56,586 | 29 | $11.1M | Research |
| Duenwald Transportation, Llc. | Transportation and Warehousing | $55,600 | $55,915 | 8 | <$5M | Research |
| 212 Truck & Trailer Repairs, LLC | Other Services (except Public Administration) | $54,717 | $54,959 | 4 | <$5M | Research |
| Eastside Equipment, LLC | Wholesale Trade | $49,000 | $49,295 | 5 | <$5M | Research |
| Cross Country Veterinarians INC | Professional, Scientific, and Technical Services | $45,710 | $45,933 | 5 | <$5M | Research |
| Brent Forest | Construction | $45,125 | $45,321 | 8 | <$5M | Research |
| Forest Excavating | Construction | $43,700 | $44,003 | 6 | <$5M | Research |
| Hovde Physical Therapy Clinic LLC | Health Care and Social Assistance | $43,530 | $43,755 | 5 | <$5M | Research |
| Northern Skies Outfitters Canada LLP | Accommodation and Food Services | $43,505 | $43,684 | 3 | <$5M | Research |
| Zachary Hovde | Construction | $40,306 | $40,390 | 10 | <$5M | Research |