| Dakota Provisions, LLC | Manufacturing | $8,962,400 | $9,045,394 | 500 | $176.5M |  Research |
| Huron Regional Medical Center, Inc. | Health Care and Social Assistance | $3,788,100 | $3,815,914 | 234 | N/A | Research |
| Our Home INC | Health Care and Social Assistance | $972,394 | $977,935 | 130 | N/A | Research |
| Ellwein Brothers | Wholesale Trade | $882,229 | $890,978 | 57 | $14.7M | Research |
| Horizontal Machining and Manufacturing, Inc. | Manufacturing | $756,200 | $761,598 | 66 | $16.1M | Research |
| Huron Sd Skilled Nursing Facility LLC | Health Care and Social Assistance | $733,505 | $736,765 | 110 | $18.7M | Research |
| Community Counseling Services | Health Care and Social Assistance | $659,800 | $667,266 | 67 | N/A | Research |
| Prostrollo Motor Sales Inc. | Retail Trade | $614,517 | $619,604 | 48 | $12.1M | Research |
| Prostrollo Motor Sales, Inc. | Retail Trade | $614,000 | $619,202 | 43 | $10.8M | Research |
| American Trust Insurance, LLC | Finance and Insurance | $600,700 | $605,539 | 40 | $20.6M | Research |
| Advanced Sunflower, LLC | Agriculture, Forestry, Fishing and Hunting | $549,000 | $556,084 | 44 | <$5M | Research |
| Skyways Ltd. | Transportation and Warehousing | $546,011 | $554,717 | 25 | $6.3M | Research |
| Skyways, Ltd. | Transportation and Warehousing | $546,000 | $549,696 | 42 | $10.6M | Research |
| Nta, Ltd | Transportation and Warehousing | $476,392 | $480,817 | 41 | $8.3M | Research |
| Ovb Holdings, LLC | Manufacturing | $468,200 | $472,232 | 42 | $11.0M | Research |
| Lankota Group, Inc. | Manufacturing | $449,900 | $452,399 | 39 | $10.2M | Research |
| Ovb Holdings LLC | Manufacturing | $425,200 | $427,432 | 45 | $11.8M | Research |
| Huron Area Center for Independence | Health Care and Social Assistance | $400,000 | $402,871 | 300 | N/A | Research |
| Tschetter & Hohm Clinic, P.c. | Health Care and Social Assistance | $351,000 | $353,642 | 25 | $7.8M | Research |
| Protective Coating Specialists, Inc. | Manufacturing | $301,500 | $304,176 | 39 | $10.9M | Research |
| Protective Coating Specialists, Inc. | Manufacturing | $301,500 | $302,706 | 29 | $8.1M | Research |
| Huron Energy, LLC | Manufacturing | $273,822 | $275,457 | 21 | $20.8M | Research |
| Midland Contracting Inc. | Construction | $257,500 | $259,603 | 25 | $7.7M | Research |
| Midland Contracting INC | Construction | $257,295 | $258,617 | 25 | $7.7M | Research |
| Asphalt Paving & Materials Co. | Manufacturing | $250,200 | $253,654 | 16 | $15.9M | Research |