| First Christian Church | Other Services (except Public Administration) | $144,300 | $164,399 | 14 | N/A |  Research |
| Animal Care Hospital Pllc | Professional, Scientific, and Technical Services | $142,810 | $143,659 | 10 | <$5M | Research |
| Dyersburg Family Eye Care Pllc | Health Care and Social Assistance | $140,360 | $141,226 | 10 | <$5M | Research |
| Ashley & Arnold | Professional, Scientific, and Technical Services | $140,000 | $141,544 | 1 | <$5M | Research |
| Los Portales - Dyersburg | Accommodation and Food Services | $136,600 | $138,190 | 23 | <$5M | Research |
| Kenmo, LLC | Accommodation and Food Services | $135,700 | $137,053 | 40 | $7.1M | Research |
| Raging River, LLC | Accommodation and Food Services | $135,200 | $136,672 | 37 | $6.6M | Research |
| Ripley Medical Clinic, Inc. | Health Care and Social Assistance | $134,800 | $136,148 | 9 | <$5M | Research |
| Tucker Tire & Oil Co. | Retail Trade | $134,500 | $135,767 | 18 | <$5M | Research |
| Klinkhammer Acoustical INC | Construction | $132,273 | $132,986 | 9 | <$5M | Research |
| Klinkhammer Acoustical Inc. | Construction | $132,272 | $133,257 | 11 | <$5M | Research |
| Dyersburg Pediatric Dentistry, Pllc | Health Care and Social Assistance | $131,000 | $132,565 | 26 | $6.0M | Research |
| First Baptist Church | Other Services (except Public Administration) | $130,910 | $131,641 | 9 | N/A | Research |
| T Enterprises, LLC | Retail Trade | $128,876 | $129,903 | 9 | <$5M | Research |
| Grace Family Practice Clinic, P.c. | Health Care and Social Assistance | $128,400 | $129,866 | 12 | <$5M | Research |
| Sisbro Management, LLC | Accommodation and Food Services | $124,800 | $126,045 | 11 | <$5M | Research |
| Dyersburg Dental Associates | Health Care and Social Assistance | $124,725 | $125,262 | 20 | <$5M | Research |
| Memorial Services, Inc. | Other Services (except Public Administration) | $123,700 | $125,040 | 18 | <$5M | Research |
| Jason and Kathy Lineberry | Agriculture, Forestry, Fishing and Hunting | $123,300 | $124,503 | 32 | <$5M | Research |
| Dyersburg First United Methodist Church | Other Services (except Public Administration) | $122,400 | $123,236 | 26 | N/A | Research |
| Dyersburg Union Mission | Other Services (except Public Administration) | $119,665 | $120,513 | 8 | <$5M | Research |
| Green Frog Coffee Co. LLC | Accommodation and Food Services | $119,600 | $121,484 | 35 | $6.2M | Research |
| Chandler Furniture Mart | Retail Trade | $119,510 | $120,204 | 8 | <$5M | Research |
| Sonic Drive-In of Dyersburg #1 | Accommodation and Food Services | $119,300 | $120,112 | 35 | $6.2M | Research |
| Neil's Bbq & Grill INC | Accommodation and Food Services | $118,467 | $119,132 | 21 | <$5M | Research |