| Frontier Health | Health Care and Social Assistance | $2,500,000 | $2,520,205 | 300 | $69.5M |  Research |
| Industrial Electronics Service, Inc. | Manufacturing | $704,148 | $708,490 | 81 | $21.2M | Research |
| Industrial Electronics Service Inc. | Manufacturing | $664,364 | $667,797 | 65 | $17.0M | Research |
| Phillips Concrete Const. LLC | Construction | $340,900 | $345,673 | 40 | $9.3M | Research |
| Phillips Concrete Const. LLC | Construction | $329,085 | $333,449 | 40 | $9.3M | Research |
| Bailey Computing Technologies Inc. | Professional, Scientific, and Technical Services | $325,215 | $327,473 | 20 | <$5M | Research |
| Rocky Top Vapor LLC | Retail Trade | $252,900 | $253,863 | 34 | $8.1M | Research |
| Mccall Commercial Fencing INC | Construction | $245,870 | $247,938 | 28 | $9.5M | Research |
| Advanced Wireless Solutions, Inc. | Construction | $209,816 | $212,112 | 19 | $6.3M | Research |
| Richard K Moore | Construction | $209,815 | $211,179 | 15 | <$5M | Research |
| Old Schoolhouse Magazine, LLC | Information | $151,640 | $153,325 | 102 | $17.1M | Research |
| Achieve Health and Wellness | Health Care and Social Assistance | $141,700 | $142,751 | 13 | <$5M | Research |
| Appalachian Plumbing and Piping Service | Construction | $115,323 | $118,245 | 16 | $5.1M | Research |
| C & C Asset Management LLC | Professional, Scientific, and Technical Services | $98,345 | $99,391 | 18 | <$5M | Research |
| C & C Asset Management LLC | Professional, Scientific, and Technical Services | $98,345 | $98,924 | 14 | <$5M | Research |
| Matthew Crowder | Professional, Scientific, and Technical Services | $97,110 | $97,504 | 7 | <$5M | Research |
| Gray Station Neurology PC | Health Care and Social Assistance | $95,000 | $95,821 | 9 | <$5M | Research |
| Gray Station Cpas PC | Professional, Scientific, and Technical Services | $82,300 | $82,785 | 6 | <$5M | Research |
| Appalachia Business Communications of Kingsport, Inc. | Wholesale Trade | $78,133 | $78,818 | 8 | <$5M | Research |
| Appalachian Plumbing and Piping Service | Construction | $74,000 | $75,338 | 13 | <$5M | Research |
| World Concrete | Construction | $68,900 | $69,589 | 6 | <$5M | Research |
| Dr. Alan M Stevens | Health Care and Social Assistance | $65,285 | $66,136 | 8 | <$5M | Research |
| Matthew Thomas Crowder | Professional, Scientific, and Technical Services | $60,395 | $61,183 | 8 | <$5M | Research |
| Romantic Escapades | Retail Trade | $54,266 | $55,017 | 7 | <$5M | Research |
| Atfab LLC | Manufacturing | $52,758 | $53,046 | 4 | <$5M | Research |