| Tri-State Manor, LLC | Health Care and Social Assistance | $847,066 | $856,673 | 110 | $18.7M |  Research |
| Harrogate Insurance Agency | Accommodation and Food Services | $531,000 | $536,412 | 177 | $31.4M | Research |
| Family Medical Clinic of Harrogate, PC | Health Care and Social Assistance | $332,700 | $335,445 | 44 | $13.8M | Research |
| Lifeline Ambulance Service INC | Health Care and Social Assistance | $253,555 | $256,013 | 28 | $6.5M | Research |
| Harrogate Restaurant Group INC | Accommodation and Food Services | $137,300 | $138,368 | 40 | $7.1M | Research |
| Amben Enterprises, LLC | Accommodation and Food Services | $137,300 | $10,488 | 40 | $12.5M | Research |
| Harrogate Family Practice | Retail Trade | $118,500 | $119,351 | 24 | <$5M | Research |
| Family Dental Care of Harrogate PC | Health Care and Social Assistance | $102,701 | $83,027 | 7 | <$5M | Research |
| Village Shops, Inc. | Retail Trade | $96,800 | $97,894 | 14 | <$5M | Research |
| Harrogate Health Group LLC | Health Care and Social Assistance | $91,700 | $92,319 | 8 | <$5M | Research |
| Willis Paving, Inc. | Manufacturing | $91,550 | $92,061 | 14 | $13.9M | Research |
| Russell Veterinary Services | Retail Trade | $86,000 | $86,825 | 13 | <$5M | Research |
| Harrogate Hospital for Animals PC | Professional, Scientific, and Technical Services | $84,200 | $84,799 | 11 | <$5M | Research |
| Family Dental Care Harrogate,, PC | Health Care and Social Assistance | $75,800 | $76,267 | 7 | <$5M | Research |
| Harrogate Family Health Care Inc. | Health Care and Social Assistance | $68,333 | $69,119 | 12 | <$5M | Research |
| Harrogate Family Health Care | Retail Trade | $60,000 | $60,422 | 10 | <$5M | Research |
| Pump Springs Baptist Church Inc. | Other Services (except Public Administration) | $52,400 | $52,718 | 10 | <$5M | Research |
| Pinnacle Performance Physcial Therapy LLC | Health Care and Social Assistance | $46,711 | $46,920 | 6 | <$5M | Research |
| Village Market, Inc. | Retail Trade | $43,402 | $43,908 | 19 | <$5M | Research |
| C Mark Russell DDS | Health Care and Social Assistance | $43,100 | $43,393 | 3 | <$5M | Research |
| Neighborhood Foods Subway of Harrogate, LLC | Accommodation and Food Services | $41,172 | $41,474 | 14 | <$5M | Research |
| Pinnacle Performance Physical Therapy, LLC | Health Care and Social Assistance | $40,294 | $40,526 | 4 | <$5M | Research |
| Ajj Trucking Company | Transportation and Warehousing | $34,500 | $34,795 | 6 | <$5M | Research |
| A-J-J Trucking Company Inc. | Transportation and Warehousing | $31,900 | $32,060 | 10 | <$5M | Research |
| Cumberland Gap Transport Inc. | Transportation and Warehousing | $31,700 | $31,939 | 9 | <$5M | Research |