| Great Rivers Employment Aptitude and Technical Services INC | Administrative and Support and Waste Management | $1,750,000 | $1,755,082 | 273 | $43.0M |  Research |
| Jerry Lewis | Administrative and Support and Waste Management | $1,604,800 | $1,617,906 | 205 | $44.4M | Research |
| Carey Counseling Center INC | Health Care and Social Assistance | $1,475,000 | $1,484,792 | 223 | N/A | Research |
| Eurotranciatura USA LLC | Manufacturing | $1,440,700 | $1,455,507 | 184 | $45.0M | Research |
| Pml INC | Manufacturing | $1,400,000 | $1,408,860 | 172 | $170.6M | Research |
| Pml INC | Manufacturing | $1,400,000 | $1,411,238 | 172 | $170.6M | Research |
| Institutional Casework Incorporated | Manufacturing | $1,353,400 | $1,366,972 | 159 | $41.6M | Research |
| Henry County Healthcare Center | Health Care and Social Assistance | $1,300,815 | $1,310,427 | 184 | N/A | Research |
| Mccartney Produce, LLC | Wholesale Trade | $1,251,400 | $1,259,082 | 170 | $43.8M | Research |
| Henry County Healthcare Center | Health Care and Social Assistance | $1,127,700 | $1,137,975 | 76 | N/A | Research |
| Houston Tank Services LLC | Transportation and Warehousing | $1,043,077 | $153,723 | 70 | $14.1M | Research |
| Four Seasons Sales & Service, INC | Wholesale Trade | $922,050 | $932,474 | 62 | $19.0M | Research |
| Mscb, Inc. | Professional, Scientific, and Technical Services | $768,724 | $774,052 | 82 | $19.9M | Research |
| Mscb INC | Administrative and Support and Waste Management | $768,107 | $772,842 | 78 | $14.8M | Research |
| Henry Farmers Cooperative | Wholesale Trade | $706,327 | $711,455 | 58 | $14.9M | Research |
| Henry Farmers Cooperative | Retail Trade | $630,370 | $633,669 | 64 | $13.2M | Research |
| Kentucky Lake Tractor Company, LLC | Retail Trade | $575,895 | $579,030 | 39 | $8.1M | Research |
| Allegro Fine Foods INC | Manufacturing | $505,600 | $509,009 | 56 | $19.8M | Research |
| Setco Automotive NA INC | Manufacturing | $457,500 | $459,821 | 41 | $10.7M | Research |
| Setco Automotive NA INC | Manufacturing | $457,500 | $459,242 | 41 | $10.7M | Research |
| Pmb Services Inc. | Professional, Scientific, and Technical Services | $438,200 | $444,383 | 42 | $5.9M | Research |
| Dpc, INC | Professional, Scientific, and Technical Services | $386,500 | $388,830 | 26 | $5.4M | Research |
| Peppers INC | Retail Trade | $368,800 | $372,027 | 38 | $9.6M | Research |
| Henry County Hardwoods INC | Retail Trade | $323,700 | $326,406 | 41 | $8.5M | Research |
| East Wood Clinic Pllc | Health Care and Social Assistance | $320,600 | $322,408 | 31 | $9.7M | Research |