| West Tn Expediting, Inc. | Transportation and Warehousing | $1,788,481 | $1,798,967 | 160 | $32.2M |  Research |
| Lauderdale Community Hospital LLC | Health Care and Social Assistance | $1,180,196 | $1,187,213 | 102 | $20.2M | Research |
| Christian Family Medicine | Health Care and Social Assistance | $962,430 | $969,782 | 65 | $20.4M | Research |
| Best Wade Petroleum INC | Wholesale Trade | $527,827 | $530,862 | 42 | $10.8M | Research |
| Faist Light Metals Tennessee, LLC | Manufacturing | $497,900 | $501,447 | 47 | $11.5M | Research |
| Best Wade Petroleum INC | Wholesale Trade | $487,612 | $495,698 | 48 | $12.4M | Research |
| Faist Light Metals Tennessee LLC | Manufacturing | $473,119 | $474,571 | 47 | $13.1M | Research |
| Helen R Tucker Adult Developmental Center | Health Care and Social Assistance | $343,300 | $345,463 | 49 | $7.9M | Research |
| Helen R Tucker Adult Developmental Center | Health Care and Social Assistance | $275,000 | $276,288 | 49 | $8.9M | Research |
| Mid South Family Farms | Agriculture, Forestry, Fishing and Hunting | $225,122 | $228,117 | 23 | <$5M | Research |
| Mid-South Convenient Care, Pllc | Health Care and Social Assistance | $183,300 | $184,756 | 14 | <$5M | Research |
| Tennessee Medical Equipment, Inc. | Other Services (except Public Administration) | $145,278 | $146,250 | 25 | <$5M | Research |
| Syed A. A. Zaidi Md, Pllc | Health Care and Social Assistance | $140,965 | $142,382 | 17 | $5.3M | Research |
| Boothe Services INC | Construction | $135,300 | $137,498 | 19 | N/A | Research |
| Grace Broadcasting Services INC | Information | $124,210 | $126,070 | 32 | $5.4M | Research |
| Ripley Drugs LLC | Retail Trade | $121,320 | $122,240 | 9 | <$5M | Research |
| Ripley Parts & Tire ,llc | Other Services (except Public Administration) | $108,800 | $109,653 | 11 | <$5M | Research |
| Fullen Ag Company | Agriculture, Forestry, Fishing and Hunting | $97,900 | $99,179 | 8 | <$5M | Research |
| Grace Broadcasting Services, Inc. | Information | $91,800 | $93,152 | 25 | <$5M | Research |
| H&h Trucking Services LLC | Transportation and Warehousing | $88,029 | $88,949 | 10 | <$5M | Research |
| Arp Cotton Gin Company, LLC | Agriculture, Forestry, Fishing and Hunting | $83,297 | $83,744 | 6 | <$5M | Research |
| Connells Body Shop | Agriculture, Forestry, Fishing and Hunting | $83,200 | $84,114 | 10 | <$5M | Research |
| Los Portales - Ripley, LLC | Accommodation and Food Services | $83,000 | $83,966 | 10 | <$5M | Research |
| Litco Transports, LLC | Transportation and Warehousing | $82,845 | $83,364 | 8 | <$5M | Research |
| Michael Dew | Construction | $82,830 | $83,359 | 9 | <$5M | Research |