| Childress County Hospital District | Health Care and Social Assistance | $2,708,082 | $2,740,128 | 250 | N/A | AI Deep Dive |
| Flat Line, Inc. | Construction | $140,000 | $140,257 | 14 | <$5M | AI Deep Dive |
| Lott Sales Company, Inc. | Retail Trade | $132,000 | $132,796 | 41 | $6.4M | AI Deep Dive |
| Texas Panhandle Construction | Construction | $121,264 | $121,577 | 12 | <$5M | AI Deep Dive |
| Texas Panhandle Construction | Construction | $115,014 | $115,465 | 10 | <$5M | AI Deep Dive |
| Bombero Aviation LLC | Agriculture, Forestry, Fishing and Hunting | $110,675 | $111,376 | 8 | <$5M | AI Deep Dive |
| Flat Line Inc. | Construction | $99,745 | $100,070 | 15 | <$5M | AI Deep Dive |
| 4h Hotels LLC | Accommodation and Food Services | $87,270 | $87,842 | 15 | <$5M | AI Deep Dive |
| Sjs Farms a Texas General Partnership | Agriculture, Forestry, Fishing and Hunting | $83,332 | $83,807 | 4 | <$5M | AI Deep Dive |
| Reddy Hospitality, LLC | Accommodation and Food Services | $82,100 | $82,867 | 7 | <$5M | AI Deep Dive |
| Foster & Lambert, LLC | Professional, Scientific, and Technical Services | $79,769 | $80,264 | 6 | <$5M | AI Deep Dive |
| Ganesh Bhoja LLC | Accommodation and Food Services | $76,818 | $77,317 | 11 | <$5M | AI Deep Dive |
| Farmers Cooperative Gin | Other Services (except Public Administration) | $74,707 | $75,161 | 8 | <$5M | AI Deep Dive |
| Volstar, Inc. DBA Cervis Technologies | Unknown | $73,660 | $74,348 | 7 | N/A | AI Deep Dive |
| Jr Advanced Practice Group Pllc | Health Care and Social Assistance | $70,138 | $70,442 | 15 | <$5M | AI Deep Dive |
| Jr Advanced Practice Group Pllc | Health Care and Social Assistance | $70,100 | $70,484 | 15 | <$5M | AI Deep Dive |
| Cottage Village Living LLC | Health Care and Social Assistance | $64,087 | $64,411 | 16 | <$5M | AI Deep Dive |
| Cottage Village Living LLC | Health Care and Social Assistance | $64,000 | $64,416 | 16 | <$5M | AI Deep Dive |
| Kevin G Keys DDS Pllc | Health Care and Social Assistance | $63,376 | $63,989 | 5 | <$5M | AI Deep Dive |
| 4h Hotels, LLC | Accommodation and Food Services | $62,300 | $62,763 | 19 | $5.9M | AI Deep Dive |
| Eric Green DDS Pllc | Health Care and Social Assistance | $60,076 | $60,716 | 5 | <$5M | AI Deep Dive |
| Eric Green DDS Pllc | Health Care and Social Assistance | $60,075 | $60,626 | 9 | <$5M | AI Deep Dive |
| Ganesh Bhoja, LLC | Accommodation and Food Services | $55,412 | $55,821 | 14 | <$5M | AI Deep Dive |
| Pragati INC | Accommodation and Food Services | $54,977 | $55,078 | 11 | <$5M | AI Deep Dive |
| Lambert Farms | Agriculture, Forestry, Fishing and Hunting | $52,959 | $53,150 | 5 | <$5M | AI Deep Dive |