| Cypress United Methodist Church | Other Services (except Public Administration) | $192,300 | $193,243 | 66 | N/A | AI Deep Dive |
| St. Michael Medical Clinic P.a. | Health Care and Social Assistance | $192,100 | $194,411 | 20 | $6.3M | AI Deep Dive |
| Discovery Years Inc. | Health Care and Social Assistance | $191,113 | $193,050 | 15 | <$5M | AI Deep Dive |
| Little Cypress Cafe | Accommodation and Food Services | $190,250 | $192,632 | 24 | <$5M | AI Deep Dive |
| J.a. Greene Construction Services LLC | Construction | $189,617 | $190,992 | 15 | $17.1M | AI Deep Dive |
| Swan Plumbing Heating and Air INC | Construction | $188,848 | $0 | 22 | $7.0M | AI Deep Dive |
| Carls Barbque INC | Accommodation and Food Services | $188,363 | $189,994 | 31 | $5.5M | AI Deep Dive |
| Cypress Empire Electric INC | Construction | $187,500 | $189,724 | 19 | $6.3M | AI Deep Dive |
| Lauren S Campbell MD PA | Health Care and Social Assistance | $186,085 | $187,910 | 22 | $6.9M | AI Deep Dive |
| Infinity Water Systems LLC | Administrative and Support and Waste Management | $185,285 | $173,046 | 26 | <$5M | AI Deep Dive |
| Dylan Hendrix LLC | Unknown | $184,000 | $185,275 | 65 | N/A | AI Deep Dive |
| Hcb Mechanical Inc. | Construction | $182,492 | $183,337 | 14 | <$5M | AI Deep Dive |
| Speech Emporium Inc. | Health Care and Social Assistance | $182,324 | $183,658 | 18 | <$5M | AI Deep Dive |
| Arzell, Inc. | Manufacturing | $181,250 | $182,217 | 16 | $15.9M | AI Deep Dive |
| Waterengineers Inc. | Professional, Scientific, and Technical Services | $181,100 | $182,459 | 12 | <$5M | AI Deep Dive |
| Insite Architecture INC | Professional, Scientific, and Technical Services | $181,005 | $178,433 | 11 | <$5M | AI Deep Dive |
| Lauren S Campbell M. D. P.a. | Health Care and Social Assistance | $181,000 | $183,117 | 23 | $7.2M | AI Deep Dive |
| Mpact Beverage Solutions LLC | Manufacturing | $180,284 | $181,845 | 15 | $5.3M | AI Deep Dive |
| Kerry K. Johnson D.d.s. P.a. | Health Care and Social Assistance | $180,075 | $182,026 | 14 | <$5M | AI Deep Dive |
| Cypress Empire Electric Inc. | Construction | $180,000 | $181,130 | 16 | $5.3M | AI Deep Dive |
| Colexas Digital Inc. | Mining, Quarrying, and Oil and Gas Extraction | $179,600 | $181,529 | 9 | <$5M | AI Deep Dive |
| Cypress Heart and Vascular Center | Health Care and Social Assistance | $179,572 | $181,323 | 12 | <$5M | AI Deep Dive |
| Morris & Associates, Engineers, Inc. | Professional, Scientific, and Technical Services | $179,112 | $181,014 | 9 | <$5M | AI Deep Dive |
| Prause Learning Enterprises LLC | Health Care and Social Assistance | $177,870 | $179,254 | 29 | <$5M | AI Deep Dive |
| Prause Learning Enterprises, LLC | Health Care and Social Assistance | $177,800 | $178,995 | 27 | <$5M | AI Deep Dive |